ID   UTP10_CHAGB             Reviewed;        1728 AA.
AC   Q2HA26;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 10;
GN   Name=UTP10 {ECO:0000250|UniProtKB:P42945}; ORFNames=CHGG_02928;
OS   Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 /
OS   NRRL 1970) (Soil fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX   NCBI_TaxID=306901;
RN   [1] {ECO:0000312|EMBL:EAQ90993.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970;
RX   PubMed=25720678; DOI=10.1128/genomea.00021-15;
RA   Cuomo C.A., Untereiner W.A., Ma L.-J., Grabherr M., Birren B.W.;
RT   "Draft genome sequence of the cellulolytic fungus Chaetomium globosum.";
RL   Genome Announc. 3:E0002115-E0002115(2015).
CC   -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC       Involved in ribosome biosynthesis (By similarity).
CC       {ECO:0000250|UniProtKB:P42945}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC       {ECO:0000250|UniProtKB:P42945}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:P42945}.
CC   -!- SIMILARITY: Belongs to the HEATR1/UTP10 family. {ECO:0000305}.
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DR   EMBL; CH408030; EAQ90993.1; -; Genomic_DNA.
DR   RefSeq; XP_001229444.1; XM_001229443.1.
DR   AlphaFoldDB; Q2HA26; -.
DR   SMR; Q2HA26; -.
DR   STRING; 38033.XP_001229444.1; -.
DR   EnsemblFungi; EAQ90993; EAQ90993; CHGG_02928.
DR   GeneID; 4388403; -.
DR   eggNOG; KOG1837; Eukaryota.
DR   HOGENOM; CLU_001128_3_1_1; -.
DR   InParanoid; Q2HA26; -.
DR   OMA; YTNQLLF; -.
DR   OrthoDB; 524830at2759; -.
DR   Proteomes; UP000001056; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR012954; BP28_C_dom.
DR   InterPro; IPR022125; U3snoRNP10_N.
DR   InterPro; IPR040191; UTP10.
DR   PANTHER; PTHR13457; PTHR13457; 1.
DR   Pfam; PF08146; BP28CT; 1.
DR   Pfam; PF12397; U3snoRNP10; 1.
DR   SMART; SM01036; BP28CT; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Repeat; Ribonucleoprotein;
KW   Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..1728
FT                   /note="U3 small nucleolar RNA-associated protein 10"
FT                   /id="PRO_0000308500"
FT   REPEAT          540..578
FT                   /note="HEAT 1"
FT                   /evidence="ECO:0000255"
FT   REPEAT          881..926
FT                   /note="HEAT 2"
FT                   /evidence="ECO:0000255"
FT   REPEAT          986..1024
FT                   /note="HEAT 3"
FT                   /evidence="ECO:0000255"
FT   REPEAT          1191..1229
FT                   /note="HEAT 4"
FT                   /evidence="ECO:0000255"
FT   REPEAT          1235..1274
FT                   /note="HEAT 5"
FT                   /evidence="ECO:0000255"
FT   REPEAT          1622..1662
FT                   /note="HEAT 6"
FT                   /evidence="ECO:0000255"
FT   REPEAT          1683..1721
FT                   /note="HEAT 7"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1728 AA;  189220 MW;  2D2F9A42C1873877 CRC64;
     MASSLAAQLA QIAANSRTSL NAKALKATHS KSLIWEPRVA AGQTFAEIYQ LSYEGFEELC
     NLDARFAQYG ASLFSEQSQE ADRIQMNAEE NAVLDKRVDS FLHLVGSRLR LMPAIKAIEW
     LIRRFRSLTA PPRAAIVQQA TNRPELLSVI SQYTLESCRA RQEYPGLVSF WGGVMAEAAN
     GMLDKMRSGR RSIQLENDHI LLQQIGPVLS EAMVMKEVPG IQIASYMIVT ILAAKGSLND
     VALTAFMDQL VHGWNIDTYR PGLVCLCILA QHRAAKQVSS RIAKALIKVQ DLVPTLVEIS
     RQHRVDKLAN GLALAFIERL SKKGDVRSLP AINSLLSANL LRDKQIKVIY KSMLLAAHKV
     NDEVDEDGHI RKEIGSSLIS LSQTGGDVGD VIRSAIEEVD FNIEELELKL GAAIRPKLAI
     EQSSEEAGAE EGAMAVENTL SLASTFQELA KLQPSTVSCL SQDSSGLFND LCAVLLSAAA
     AESDMEKFDS IPALSRPLAT SNPFYLSFYM RVWCGPFPTL AKVAALERVK LRLKESDCAD
     KDFQAIIPYC AVALSDPAKK VRRAAADLIA VLGSLVKEQT RQVWGAKDLY GKVGAPNALD
     RDTLKALVSS VLVPSLEESV LHEAHVVAVL VSALESSKGS SGTEGGRRHL SHATRLSIFK
     FICGHVTETP LLAVKIRLLR SLNQIRSISG TSRTDLLLPL LRWWAALGHE EVIELTARES
     LDEATVDQAV VDVIIANHAA GLETAFELIN DPKTALRPHL VQAIFCRVIK MWPSMKSDTK
     SSTARFMFNI TQTLSSSEHG PVITEAVELL RKVELTTDIQ LDLIDSLQDQ VKLATEKPAN
     KRRRVSTTEQ SRSVGLQSNP ELKAALNKTT FVLELVQESD PANHPELLPS LFTTLSDLHH
     LSTLIGSELG YLQNLVLSSL LAMMPAYKDN KNLTIDASVG HGDILATCIQ KSSSPAVINA
     ALLLVASLAR TAPDVVLQSV MPIFTFMGSS EVIPPLIDTF RRRGRNVVAS TKDLLASFVT
     AYEHIPSHRK HDLFISLVQN LGPEDFLFAI LAMFVDRYAA TDNMISFTTQ MMSSFSVEIQ
     LQTLIKLLDL TSDIFKPKPS LSNVLLGGDG SEHDTQKVAT KQLNLLPHLL ANKRLKREIT
     QLAERDDMET GKIRDLYATL LESILTLATT VKNKKALYNR CGDALSNLLN LLSIAEFIKS
     VEALLDRPNV GLRQKVLRAL ELRVDSESTA DPRSREALLA FLPQLTAVIR ESDDMSYKHT
     AVTCVDKISE KYGKKDLDAV AAAAATIAGD YCLGQSSQTL RVMALLCLAS LVDVLQDGIV
     PVLPVAIPKA LDYLEQSLVG EEPNAELHNA AYAFVAALAQ HIPYMITGSY LDRLLACSNA
     SAAAALDDES SSNRTHCLQF LAKLVDPKVM YNALNQNWAS ASSCGASAVS EYLDILGMAL
     DKHSKAAVAK NVASLSTIFL SAMDLRRTVV SGQAKTAISP SELGEIETKI GDDALKMIYK
     LNDAAFRPIF SKLMEWASTG LPKNDASGRT LRLFAVYGFL DTFFGNLKSI VTSYASYIVE
     SAVQVLSSTN FQDADEKELW KWVLRTLGKC FEHDQDGFWQ APAHFGAVAP VLVEQFLNAG
     AADATEDLIP ALVELAAAAD SQEHHKELNG TLLKHLRNGQ AAVRLAVVQC QQALTVRLGE
     EWLQALPEML PYISELQDDD DEVVERENRR WIVEIEEKLG ESLDSMLQ