ID   UTP10_PICGU             Reviewed;        1819 AA.
AC   A5DGZ7;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 2.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 10;
GN   Name=UTP10 {ECO:0000250|UniProtKB:P42945}; ORFNames=PGUG_02548;
OS   Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539
OS   / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Meyerozyma.
OX   NCBI_TaxID=294746;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC       Involved in ribosome biosynthesis (By similarity).
CC       {ECO:0000250|UniProtKB:P42945}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC       {ECO:0000250|UniProtKB:P42945}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:P42945}.
CC   -!- SIMILARITY: Belongs to the HEATR1/UTP10 family. {ECO:0000305}.
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DR   EMBL; CH408157; EDK38450.2; -; Genomic_DNA.
DR   RefSeq; XP_001484819.1; XM_001484769.1.
DR   AlphaFoldDB; A5DGZ7; -.
DR   SMR; A5DGZ7; -.
DR   STRING; 4929.XP_001484819.1; -.
DR   PRIDE; A5DGZ7; -.
DR   EnsemblFungi; EDK38450; EDK38450; PGUG_02548.
DR   GeneID; 5127142; -.
DR   KEGG; pgu:PGUG_02548; -.
DR   VEuPathDB; FungiDB:PGUG_02548; -.
DR   eggNOG; KOG1837; Eukaryota.
DR   HOGENOM; CLU_001128_3_1_1; -.
DR   InParanoid; A5DGZ7; -.
DR   OMA; YTNQLLF; -.
DR   OrthoDB; 524830at2759; -.
DR   Proteomes; UP000001997; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR012954; BP28_C_dom.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR022125; U3snoRNP10_N.
DR   InterPro; IPR040191; UTP10.
DR   PANTHER; PTHR13457; PTHR13457; 1.
DR   Pfam; PF08146; BP28CT; 1.
DR   Pfam; PF12397; U3snoRNP10; 1.
DR   SMART; SM01036; BP28CT; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   PROSITE; PS50077; HEAT_REPEAT; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..1819
FT                   /note="U3 small nucleolar RNA-associated protein 10"
FT                   /id="PRO_0000308511"
FT   REPEAT          1779..1817
FT                   /note="HEAT"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1819 AA;  203250 MW;  793B7A585492FBA9 CRC64;
     MSLSQQLKQI NEKSASVALD RKSRSKLHSK SLIFAPKVAA TQDYDYLHSV GVDGLTELCT
     IDSRFLKFQQ TLFADSTVNF DRNVQTKEIV DNLDASIAAF LNLVSPFYPL SPAVKAVEWL
     VRRFYINIHN SEALILTCLP HYQSQIFARV MNVIPKSSWP PIFNWLNGYR DMSKNPPSSS
     ILKAFRNDYQ LFKLYSEYIT QQVSVETVYK EQLVFYLTNT IQLLASYSTD IEKLNEVYLP
     VILEVIGKFL LASNTSLDHD IKIAAYTLMS VVVSLVPLAD DVHISLTRSI LQVPGAFDPQ
     LKRQTMIILA QTWQRYTGAK FDFEFFNTIP LDSLLKDNLL ESLVHEGFDF NNFLLALISS
     TNDKRTLSLA KLFKIERANE AVATTFISRL IDAASFKPDT EARASIVAAF EAMLAGSRDT
     LVEYLGSKKE PMSLADLEMV LLTTLSSSDV DDSEINVAQS DEVQEANGSS NSEPVTLDGV
     KSHTKSFLFQ CEDFNDLSRL LVSFLAPFES NSYANQIAKF CAAVFTGPNA SITFTLRCSL
     TPIIPLKVRL ACLICLKRKL KELAKSGDTK LHLILPILIL GLYDDHQSIR AGFAESIHSL
     STPSASKNAS IFLEDEMYAD VAASNKVLIS PKDGDSLINL LTSTDSLLKE TVLDKTRLVS
     VLFEVVFKAQ QPSKKFGLVC QTFFIAQWSQ LPFAAVFKSL IFKIMSGRNI TAECPSRESF
     IKGDVAGLFS GYEAWMASAQ ESKLDFESDI VSPLVNLVGG QDELSTPNSS EIDEVGWLIK
     ATDFTKCPVI QVAATKRVTQ VFEFLKPEDK VRLYSKFIEL QASDDELNFD AQEILQAMPL
     DFNSALTLLK NFQLVAQIPE QQIPKRRRRS SNSSKQTMAH EELVSIASVH LRKLTIVLDL
     LEYNLRKNLK EIKPELLSSF FGILTDLEYL GHDGDMPVLY TQEVLATCML LAVKHIKAIN
     ENGSGRISID SNSVRADLIV NTIRSSNSPQ IQNRLLLVIA ELASLAPEII LHSVMPIFTF
     MGAHTIRQDD EFSSFALQDT IAKVVPALAK SGASSFSNEI EFLLTSFVTA FQHIPRHRRV
     KLFSSLSKTL GAGNSIHTIL FLSGVQYASL FGKGKHGDCL SLLEFTQGYM KQFQASEQLS
     AIHKFCTLWQ LVPTKPLDPD SDEFRNLNSR PIFGASILSL NDTELVELKA GLITFIDSLL
     QTDEESVGYL QLRVNQLLLD SHSTDGEKTI IIDGCKNVAS LLLGSLDNFG QVSKMTKVSD
     NLYQFLDDIL SLLPLVYFLD SIIDVLKNPM GVDRVAINFA RLAGNKIENE LTASNLDEQI
     QFSLFEKLVP VLISGIKSNQ DAEISQAYMD ATAQAVAKLG NCTTCFNEAK NVSVLNECLS
     ILTSESGLKS SKPECIISSM NCISSIINIM GVKAIGFFPK IFEPTVEIWK TTKTNEEDMQ
     LVQTSVLLLF AQLVKKLPAF VTSKLDSIFT CTIGSLAVDA TVRSSILSSI VEYVDTAYVL
     KALCNVWGEI SKSDNAEVIG LYLGAMEKTI DQLEKKSAIS QATLFIKWMI KAFEFRSSVS
     KSSQDFDTNT IHRLESSFHS CGLRYVMKLN DKTFRPLFAG LVRWAVNGEG STSDTDEVSR
     YIAFFRFFNK VQEQLKSIIT SYYSYLIDPV SSLLKRIDTM EDSINLKRMV FNSLTSSFKY
     DQDDFWSQPS RFESICGPLL QQIPTIENSI GKYLVKCVSA FVVNVSSEEH NEKLVHGLIH
     YISNEHSTTN SHTKTWTIRI LKSVFQKMGD QWLSYLPTLI PYIAELLEDD DEDVELEVRK
     GLVKVLENVL GEPLDRYLN