ID   UTP10_USTMA             Reviewed;        2251 AA.
AC   Q4P937; A0A0D1C550;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 10;
GN   Name=UTP10 {ECO:0000250|UniProtKB:P42945}; ORFNames=UMAG_03376;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC       Involved in ribosome biosynthesis (By similarity).
CC       {ECO:0000250|UniProtKB:P42945}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC       {ECO:0000250|UniProtKB:P42945}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:P42945,
CC       ECO:0000255}. Membrane {ECO:0000255}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the HEATR1/UTP10 family. {ECO:0000305}.
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DR   EMBL; CM003147; KIS68812.1; -; Genomic_DNA.
DR   RefSeq; XP_011389758.1; XM_011391456.1.
DR   AlphaFoldDB; Q4P937; -.
DR   SMR; Q4P937; -.
DR   STRING; 5270.UM03376P0; -.
DR   PRIDE; Q4P937; -.
DR   EnsemblFungi; KIS68812; KIS68812; UMAG_03376.
DR   GeneID; 23563845; -.
DR   KEGG; uma:UMAG_03376; -.
DR   VEuPathDB; FungiDB:UMAG_03376; -.
DR   eggNOG; KOG1837; Eukaryota.
DR   HOGENOM; CLU_001128_0_0_1; -.
DR   InParanoid; Q4P937; -.
DR   OMA; NDVMWKQ; -.
DR   OrthoDB; 524830at2759; -.
DR   Proteomes; UP000000561; Chromosome 8.
DR   GO; GO:0030686; C:90S preribosome; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR   GO; GO:0034455; C:t-UTP complex; IBA:GO_Central.
DR   GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   GO; GO:0045943; P:positive regulation of transcription by RNA polymerase I; IBA:GO_Central.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR012954; BP28_C_dom.
DR   InterPro; IPR022125; U3snoRNP10_N.
DR   InterPro; IPR040191; UTP10.
DR   PANTHER; PTHR13457; PTHR13457; 1.
DR   Pfam; PF08146; BP28CT; 1.
DR   Pfam; PF12397; U3snoRNP10; 1.
DR   SMART; SM01036; BP28CT; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Membrane; Nucleus; Reference proteome; Ribonucleoprotein;
KW   Ribosome biogenesis; rRNA processing; Transmembrane; Transmembrane helix.
FT   CHAIN           1..2251
FT                   /note="U3 small nucleolar RNA-associated protein 10"
FT                   /id="PRO_0000308513"
FT   TRANSMEM        962..982
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1460..1480
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REPEAT          945..983
FT                   /note="HEAT"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   2251 AA;  244327 MW;  F7F1FA6FB355CB01 CRC64;
     MTSSLAAQLA NVRSLNAERL TSSASLVKHT SYLFPPKTAA QQDLFTVHAL GASGWTELSA
     ENASLQRWSQ SSLLFGDESR SMDRLMLPKE ENDTIDKAVD EFLHLAAPFL LSKGASKCLE
     WLVRRFRVHE FSVEHVLAAF LPYHDTQQFA RMLSICKLDG KPHLQFLLSV KKTASPLPAG
     VLHTAILAPA TTTASLDLLR WISGLLANDV SYQLQVSPHR ALVNFWTSTL VQICAARSRP
     DDNQQLAGLS KSTSNSKKST KTRAADAQAI LTILLPSAVR VAGTASLGQD AQMGGFMLLC
     TISQSFPLSK EAIQGVLTSL AKLLSTSHVV PAVNRALIAC AFALCASPIA TSDPLTTQST
     SADRLIPDSL TAVLVSSTDA SNCIGALAKS YDARAFLAHF IAALTARLSH APSADLLSAI
     LRGPAVQDNL CIQASELLLR LRLGASVGSS QAQDTAFEAH FVNDAVNEAH RNRLRVLQTV
     RNRKPHVFDT ALHNCTRKHQ SEAVIAAIWQ TVQAVLAIES GIPLQDASQG KHDEQGRSDI
     LWLSIHSADA SQRCLALKQL FKDIKEGRAL PQDTMVREAL HARIQDSSID VLQILYSQPA
     AVLNAFDART LLTMIAEALD EGRIAVDRFT QHLSFLLNPY LKEHADANDQ VARRAVWPHL
     LHSPSRLANA SSAIKLLSQS SNTNGVLSLI ASFAAKYEDP THVNDAIARA VAAHLVSVSA
     EDRKDWVDFL TSTARPSQTT ATASRDLALL SLIHLSDKIA GDDLVSLSET ILRNVVLPSL
     TVLGAPTAEH LQQLSSLTLN DALTSLQHVK QLETLFKHAA TEQSAILLVN HLLVQLVRRA
     EVPAFDTYLT SQVSPELQRA KTILTSLYSV INTAPLPTSL SKLLLRILLF KLGDSSLPFL
     ASIWTNTSGS YTAAVRLAAL RHADAYLQAQ VQAISQQEAR DFQVVVPLLL TALADAEAAI
     RLAAIACLAH ILAICKYAGD LAKASKKKAK ELDIFGYESF HGAATSDPMQ YIDLVSLAPY
     LEQIIESKSA FRNDAALLPR LHGELLQIGR QDGRKEVGHK HAMVCFIVSH ILCIDSLPSR
     LVLLQSLSRV SDAAKLEMLL PLIREVVEGN VATATNGLRN VEDRELYLEL LFASYDRGCR
     DVVEQAASGA WPLYLKALEG RDGKRQVQKA AVRALDKAGL FATLSPIMRK ESYLHLASVV
     ADPSVPASPE VASALRELKV DSAILIAVLS ELREAITSKA LSGPESKRAR TSLSSDETMK
     RTCAILAAVL ESAVGSRLMC TPALLYELFE VLRVAVDLHS GLLATNGEHM MQLAMSCIEK
     LVGSLPKSAA TIPAEIAQAL RADTIVSVIK SSNNPQTFQH ALLLLSKIAS IAPETVLHNV
     MPIFTFVGST VLQRDDAFSF SVVEKVLQSI VPALVNSFRA SDAAKKSKFA LLCEARAFVR
     IFTDAAAHVP RHRRQTFFRL LVDILGADDF AAAVAMLLVD RSAHKIVKQS RSDAEQTLQL
     PLAVVSPHSA MVQVRVLHQV WEEVLRIWAN RDETESLSEL VFLDRAGRLD KEHVDHESEP
     LRQIQALIML IRQVLVSKAF ADQMGKVASN QIGEELETFI RLALETVASV RSSQPTIAGL
     ALEVLDAAMP FAPVDNVLAV VSGLVEGQDV AHRTSGFSLF ASRVGAMSPT STDRAAVAAY
     TPTIVKEAIE VIATSLATPP AGADAESLRQ AALDALKTVS SSAQTAEHAT LASALPTLIK
     LGKTSAESER VQRAVPWAAR ISVFSITRRL ATKLGPRLIP HIAALVPFCL SVISRSASAT
     VGSADAVQDE SENEKGRAAA AGVNSNKAVL RTGALDTLTG LFGSVSTFMS SYVAQIIRMS
     ISPELKKAMS SVSGSSTASE RSLNLLVSTL IRKTVANQLF EATFKVWDQE LAVAENDDAV
     ERLVGISEFL GRALRQSDRE AISATYKLVY RFLLRALDLG RINVAGNGKL SRASIARIET
     SLVSLPFMRM VLKLNEASFR PLFMRMFDWA VLDLVDGDEV DVHSEETDAI VARQVVLFKT
     FNALSETLRS LVSSYYAVLL DQVIELLSTW SKLAARATVA HQSMQRELWN EVMRSIQLSA
     KHDEGIFWNP SRVAKIIGPI LDQMNLLNAS WNDKKRFIEA EEFVGAVAPV VVGLLNNVND
     QATLKLFNSS LLQRASATRA TNSSLIRSTA TQLLTHMWAA QNDQLLALVP ETIAQLSELL
     EDDHQPIVAY ANQFRSHIEA ALGESLESYL T