UTP10_YARLI
ID UTP10_YARLI Reviewed; 1635 AA.
AC Q6C457;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 92.
DE RecName: Full=U3 small nucleolar RNA-associated protein 10;
GN Name=UTP10 {ECO:0000250|UniProtKB:P42945}; OrderedLocusNames=YALI0E29506g;
OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Yarrowia.
OX NCBI_TaxID=284591;
RN [1] {ECO:0000312|EMBL:CAG80159.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIB 122 / E 150;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC Involved in ribosome biosynthesis (By similarity).
CC {ECO:0000250|UniProtKB:P42945}.
CC -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC {ECO:0000250|UniProtKB:P42945}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250|UniProtKB:P42945,
CC ECO:0000255}. Membrane {ECO:0000255}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the HEATR1/UTP10 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CR382131; CAG80159.1; -; Genomic_DNA.
DR RefSeq; XP_504555.1; XM_504555.1.
DR AlphaFoldDB; Q6C457; -.
DR SMR; Q6C457; -.
DR STRING; 4952.CAG80159; -.
DR EnsemblFungi; CAG80159; CAG80159; YALI0_E29506g.
DR GeneID; 2911923; -.
DR KEGG; yli:YALI0E29506g; -.
DR VEuPathDB; FungiDB:YALI0_E29506g; -.
DR HOGENOM; CLU_001128_3_1_1; -.
DR InParanoid; Q6C457; -.
DR OMA; YTNQLLF; -.
DR Proteomes; UP000001300; Chromosome E.
DR GO; GO:0030686; C:90S preribosome; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR GO; GO:0034455; C:t-UTP complex; IBA:GO_Central.
DR GO; GO:0030515; F:snoRNA binding; IBA:GO_Central.
DR GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0045943; P:positive regulation of transcription by RNA polymerase I; IBA:GO_Central.
DR Gene3D; 1.25.10.10; -; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR012954; BP28_C_dom.
DR InterPro; IPR022125; U3snoRNP10_N.
DR InterPro; IPR040191; UTP10.
DR PANTHER; PTHR13457; PTHR13457; 1.
DR Pfam; PF08146; BP28CT; 1.
DR Pfam; PF12397; U3snoRNP10; 1.
DR SMART; SM01036; BP28CT; 1.
DR SUPFAM; SSF48371; SSF48371; 2.
PE 3: Inferred from homology;
KW Membrane; Nucleus; Reference proteome; Ribonucleoprotein;
KW Ribosome biogenesis; rRNA processing; Transmembrane; Transmembrane helix.
FT CHAIN 1..1635
FT /note="U3 small nucleolar RNA-associated protein 10"
FT /id="PRO_0000308514"
FT TRANSMEM 1141..1161
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1288..1308
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 781..803
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1635 AA; 181746 MW; 4508508AA45E20DD CRC64;
MSTLSQQLSQ LGGGSTVDRT WKLKQHSKSL IYEPQVAQDQ DFSFIHAVGV EGLRDLVSLD
SRFAQFENNL FSDTSIDVDR YVQTQEQNDL LDKAISAFLS LIGPYLMLSP AVKALEWLVR
RFHVNQMNAE QLLLCVLPYY DQDIYLRVAD VIIKLPPLFV FLNKSKSAAQ NPPRNLLIRA
FSADMRLFEL ITEYIVGQTT TKTSYQRQLS FWSQFAIYGL VADKADPERM LEIYLPALAK
LVVTIDTDCQ IAAYMVLTVL GNKMPLNKEV FNALVETIAA NWTQKAIKSG ILCITQMYQQ
KQEPEVLPTS VMTALNKAGF QPSDVVALSQ KYKMALFTLG YCMALLRNPD AANFKGLEEI
ISNTQFGSNE STFLMRYIVD WALAKETNTS VAALAAPVIA KWVTRGETVP ELDQLELKLQ
TVFTEAAVEE MEVEEIQEDV DVESLVEQAK KAASQTTTYF STKTSENYAE LSKIFVQLIE
RGYTMDKFVS MFSSDIASLT FFARIWASPS PLLARLAAVE AAKTIITAAG EADFQNLIPY
TCIALSDASQ RVRKAAASFA EVLKSKQNKK PIWGVEKIYT NDCSYLGSGD VTVLLNALSL
EECILDESFV IRQVSDMISK KKGYKSAFST AVLAYLGSHA VSQEIIAIRT SLLTLVTSSE
EPIVPTTKVV EPLYINPPND LAYITELIRT VTDKTGIKFL ESLIKNDSPI YDEVCDIVTQ
RLVKLWPTLK GDAHLGLFRF FVDLSLDKDV PFDSLDVLAH VDVPTKVFIS LLDDCKVEQN
TTSMDAPSDE STKRRRRSSS STVRNLLQGK LHHIAERNLR KVSLVLELLV ASKTTDDALL
GPLFTQLGEI LTLGTDSNLP IDYCQSLLAD VLLNIIRANQ HDGASIDRDI RVDIVVSAIR
TASNAQIQNK YLLLVAELAT VAPTLVLHSV MPIFTFMGAN TLRQDDDFSV HVIEQTVARI
VPCLAGNTDK VDMLLVSFVT AFPHIPQHRR VKLFGELVRA LDASGTKDAL ATLLFLFAQK
SAELKTARKT SEVSAIAKFC DSLFKLFDAS KQLAVVLPYV TLVQELYAII ATDPKTKEKE
KKTRRQIFLQ VDKELEVSPI DFLVVLLESR ILPLQAGLVQ SPEALKIAEN VLTVLIESQY
PELLNVILSL LPLPLFVTVA GRLGSSVYKT VLARFSSGSI EEEDTKASDT LLESLHSLLK
STTDTGDLVL LLQIVETVAS GFPKCSDALL VTCAGEAVAQ LKNSDDDVFI QAVSVLSSLC
LRLGARMIGL FPATISSVLA RDSSDNLIAL SVLALFATFI KRLPSFMVSS LPKIFEFALK
CPADTDTRKQ LFVVCVETMD SRVVLQTLCD SWKFVEGFEN ARLFADTLDL AVAEADKKQI
HSKADSLITL CLEAFDSSLK LEANTAARVQ NLFIKCLIAI VLKLNDKTFR PLFVKIVDWN
TPERSTLLFK IVCRLQENLK SIVTSYYGYI IDLALEILNK ASAITPALQR NILSSLYSSF
RFDREEFWNN EERFTKISDA LGAQFPYLTK VAPENSKLLI KAVVALCELA SEDQKKQLND
MMIKLLRQAP LYGSRCFAAL FNNVGEEFLP FLPQLVPQIA ELLESEDEKV ESAVRAELIP
AVEEVLGESL DRYLA