UTP13_SCHPO
ID UTP13_SCHPO Reviewed; 777 AA.
AC Q9USN3; Q9Y7U2;
DT 21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-FEB-2006, sequence version 3.
DT 25-MAY-2022, entry version 135.
DE RecName: Full=Probable U3 small nucleolar RNA-associated protein 13;
DE Short=U3 snoRNA-associated protein 13;
GN Name=utp13 {ECO:0000250|UniProtKB:Q05946};
GN ORFNames=SPCC16A11.02, SPCC63.16;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:CAB40020.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC {ECO:0000250|UniProtKB:Q05946}.
CC -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC {ECO:0000250|UniProtKB:Q05946}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
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DR EMBL; CU329672; CAB40020.1; -; Genomic_DNA.
DR PIR; T41075; T41075.
DR RefSeq; NP_587989.2; NM_001022980.2.
DR AlphaFoldDB; Q9USN3; -.
DR SMR; Q9USN3; -.
DR BioGRID; 275903; 1.
DR STRING; 4896.SPCC16A11.02.1; -.
DR MaxQB; Q9USN3; -.
DR PaxDb; Q9USN3; -.
DR EnsemblFungi; SPCC16A11.02.1; SPCC16A11.02.1:pep; SPCC16A11.02.
DR GeneID; 2539337; -.
DR KEGG; spo:SPCC16A11.02; -.
DR PomBase; SPCC16A11.02; utp13.
DR VEuPathDB; FungiDB:SPCC16A11.02; -.
DR eggNOG; KOG0319; Eukaryota.
DR HOGENOM; CLU_009276_0_0_1; -.
DR InParanoid; Q9USN3; -.
DR OMA; PYVQRHF; -.
DR PhylomeDB; Q9USN3; -.
DR Reactome; R-SPO-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR PRO; PR:Q9USN3; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0030686; C:90S preribosome; IBA:GO_Central.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0032040; C:small-subunit processome; ISO:PomBase.
DR GO; GO:0034511; F:U3 snoRNA binding; IBA:GO_Central.
DR GO; GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR GO; GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR Gene3D; 2.130.10.10; -; 5.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR013934; SSU_processome_Utp13.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_repeat.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR Pfam; PF08625; Utp13; 1.
DR Pfam; PF00400; WD40; 9.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 12.
DR SUPFAM; SSF50978; SSF50978; 2.
DR PROSITE; PS00678; WD_REPEATS_1; 5.
DR PROSITE; PS50082; WD_REPEATS_2; 8.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Repeat; rRNA processing; WD repeat.
FT CHAIN 1..777
FT /note="Probable U3 small nucleolar RNA-associated protein
FT 13"
FT /evidence="ECO:0000305"
FT /id="PRO_0000223893"
FT REPEAT 14..57
FT /note="WD 1"
FT /evidence="ECO:0000255"
FT REPEAT 59..98
FT /note="WD 2"
FT /evidence="ECO:0000255"
FT REPEAT 101..140
FT /note="WD 3"
FT /evidence="ECO:0000255"
FT REPEAT 143..184
FT /note="WD 4"
FT /evidence="ECO:0000255"
FT REPEAT 187..226
FT /note="WD 5"
FT /evidence="ECO:0000255"
FT REPEAT 228..270
FT /note="WD 6"
FT /evidence="ECO:0000255"
FT REPEAT 362..401
FT /note="WD 7"
FT /evidence="ECO:0000255"
FT REPEAT 408..452
FT /note="WD 8"
FT /evidence="ECO:0000255"
FT REPEAT 463..504
FT /note="WD 9"
FT /evidence="ECO:0000255"
FT REPEAT 506..544
FT /note="WD 10"
FT /evidence="ECO:0000255"
FT REPEAT 547..588
FT /note="WD 11"
FT /evidence="ECO:0000255"
FT REPEAT 590..628
FT /note="WD 12"
FT /evidence="ECO:0000255"
SQ SEQUENCE 777 AA; 85872 MW; C543B426D560AA60 CRC64;
MAPIGEKKRF ELEKSIEPIY TGGPVAFDSN EKILVTALTD RIIGTRSETG ERLFSIKKDE
DDYVTALAIT SDSKKLIAAF RSRLLTIYEI PSGRRIKSMK AHETPVITMT IDPTNTLLAT
GGAEGLVKVW DIAGAYVTHS FRGHGGVISA LCFGKHQNTW VLASGADDSR VRLWDLNSSR
SMAVFEGHSS VIRGLTFEPT GSFLLSGSRD KTVQVWNIKK RSAVRTIPVF HSVEAIGWVN
GQPEEKILYT AGEGNLILAW DWKSGSRLDP GVDTTHSETN AIIQVVPFSE NTLLSVHSDL
SLLLRKRVPG EGFITIKKLN GSFDEVIDCA WIGDDHLAVC SNTEFIDVIS TDGTQVFGVL
EGHTDIVLTL DSSEDGVWLA TGAKDNTVRL WNLNIEDNVY KCIHVFTGHT ASVTAVALGP
LDVNGYPTFL ASSSQDRTLK RFNLGSQLNK SDFSNRAVWT IKAHDRDVNA IQVSKDGRII
ASASQDKTIK LWDSSTGEVV GVLRGHRRGV WACSFNPFSR QLASGSGDRT IRIWNVDTQQ
CVQTLEGHTG AILKLIYISQ GTQVVSAAAD GLVKVWSLSS GECVATLDNH EDRVWALASR
FDGSLLVSGG ADAVVSVWKD VTEEYIAKQA EELERRVEAE QLLSNFEQTE DWQQAIALAL
SLDRPHGLLR LFERVMTAPH QPNSITGNKD VDNVLVQLPD HQLIILFQRI RDWNTNSKTS
MVAQRLLRLL LHSYSPEHLL KLSGIKDILD SMIPYTDRHL ARVNDLIEDS YIVDYVI
