ID   UTP15_CHICK             Reviewed;         520 AA.
AC   Q5F3D7;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 15 homolog;
GN   Name=UTP15; ORFNames=RCJMB04_20m16;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Ribosome biogenesis factor. Involved in nucleolar processing
CC       of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA
CC       transcription by RNA polymerase I. {ECO:0000250|UniProtKB:Q8TED0}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q8TED0}.
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DR   EMBL; AJ851713; CAH65347.1; -; mRNA.
DR   RefSeq; NP_001012624.1; NM_001012606.1.
DR   AlphaFoldDB; Q5F3D7; -.
DR   SMR; Q5F3D7; -.
DR   STRING; 9031.ENSGALP00000029076; -.
DR   PaxDb; Q5F3D7; -.
DR   PRIDE; Q5F3D7; -.
DR   Ensembl; ENSGALT00000029725; ENSGALP00000029076; ENSGALG00000013510.
DR   GeneID; 426152; -.
DR   KEGG; gga:426152; -.
DR   CTD; 84135; -.
DR   VEuPathDB; HostDB:geneid_426152; -.
DR   eggNOG; KOG0292; Eukaryota.
DR   eggNOG; KOG0310; Eukaryota.
DR   GeneTree; ENSGT00390000004228; -.
DR   HOGENOM; CLU_021102_4_1_1; -.
DR   InParanoid; Q5F3D7; -.
DR   OMA; WKEHKQP; -.
DR   OrthoDB; 621827at2759; -.
DR   PhylomeDB; Q5F3D7; -.
DR   TreeFam; TF319494; -.
DR   Reactome; R-GGA-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   PRO; PR:Q5F3D7; -.
DR   Proteomes; UP000000539; Chromosome Z.
DR   Bgee; ENSGALG00000013510; Expressed in spermatocyte and 13 other tissues.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0045943; P:positive regulation of transcription by RNA polymerase I; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR018983; U3_snoRNA-assocProt_15_C.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF09384; UTP15_C; 1.
DR   Pfam; PF00400; WD40; 4.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Repeat; rRNA processing; WD repeat.
FT   CHAIN           1..520
FT                   /note="U3 small nucleolar RNA-associated protein 15
FT                   homolog"
FT                   /id="PRO_0000051324"
FT   REPEAT          36..75
FT                   /note="WD 1"
FT   REPEAT          78..117
FT                   /note="WD 2"
FT   REPEAT          120..159
FT                   /note="WD 3"
FT   REPEAT          162..202
FT                   /note="WD 4"
FT   REPEAT          204..242
FT                   /note="WD 5"
FT   REPEAT          246..285
FT                   /note="WD 6"
FT   REPEAT          287..326
FT                   /note="WD 7"
SQ   SEQUENCE   520 AA;  58393 MW;  A79B7E018969940D CRC64;
     MASYKPVVIP AVPKLGEKIT QDTLYWRGYK TPVQIKEFGA INKIDFSPVP PYNYAVTASS
     RVHIYGRYSQ EPIKTFSRFK DAAYCATYRD DGKLLVAGSE EGSIRLFDIS GRAPLRQFDG
     HTKAVHVVGF LSDKYRIFSG GDDYSSSLWD IPSATEIVSY SEHSDYVRCG CASKLNGDVF
     ITGSYDHTVK VFDARTKSSV MTIEHGHPVE SVLLFPSGGL LVSAGGRYVK VWDVLKGGQL
     LVSLKNHHKT VTCLCLNSSG QRLLSGSLDR HVKIYSTTSY KVVHSFNYAT SILSLALSPE
     DETIIVGMTN GVLNVKHRKP EESKEKSQKK RQPAYRTYVK GRNYMPKQED FFVSKPGRCI
     MRKYDKLLKS FQSSKALDAV LEPHIRLYTP EVTVAVMQEL NRRGTLRSAL AGRDEKQISL
     LLTFVTRRVI EPRFTPVLIT VADMITDIYQ PVVGQSALVD KQFLRLQEAI GREIDYQEEL
     LEVLGMMDAL FATLTEKRAT YLEENKSNGL TKTLDQDISI