ID   UTP15_XENTR             Reviewed;         515 AA.
AC   Q5XGE2;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 15 homolog;
GN   Name=utp15;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Ribosome biogenesis factor. Involved in nucleolar processing
CC       of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA
CC       transcription by RNA polymerase I. {ECO:0000250|UniProtKB:Q8TED0}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q8TED0}.
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DR   EMBL; BC084500; AAH84500.1; -; mRNA.
DR   RefSeq; NP_001011103.1; NM_001011103.1.
DR   AlphaFoldDB; Q5XGE2; -.
DR   SMR; Q5XGE2; -.
DR   STRING; 8364.ENSXETP00000059937; -.
DR   PaxDb; Q5XGE2; -.
DR   DNASU; 496516; -.
DR   GeneID; 496516; -.
DR   KEGG; xtr:496516; -.
DR   CTD; 84135; -.
DR   Xenbase; XB-GENE-491403; utp15.
DR   eggNOG; KOG0310; Eukaryota.
DR   InParanoid; Q5XGE2; -.
DR   OrthoDB; 621827at2759; -.
DR   Proteomes; UP000008143; Chromosome 1.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0045943; P:positive regulation of transcription by RNA polymerase I; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 2.
DR   InterPro; IPR018983; U3_snoRNA-assocProt_15_C.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF09384; UTP15_C; 1.
DR   Pfam; PF00400; WD40; 4.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 2.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Repeat; rRNA processing; WD repeat.
FT   CHAIN           1..515
FT                   /note="U3 small nucleolar RNA-associated protein 15
FT                   homolog"
FT                   /id="PRO_0000051327"
FT   REPEAT          36..75
FT                   /note="WD 1"
FT   REPEAT          78..117
FT                   /note="WD 2"
FT   REPEAT          120..159
FT                   /note="WD 3"
FT   REPEAT          162..202
FT                   /note="WD 4"
FT   REPEAT          204..242
FT                   /note="WD 5"
FT   REPEAT          246..285
FT                   /note="WD 6"
FT   REPEAT          287..326
FT                   /note="WD 7"
SQ   SEQUENCE   515 AA;  58267 MW;  55C157F75C804142 CRC64;
     MSGYKPVAIP TYPKLGEKIT QDTLYWKRYK TPVQIKEFGA VTKIHFSPVQ PCTYAVTSST
     RIHLYGQYSQ EPIKTFSRFK DTAYCGTFRG DGKLLAAGCE DSVVQLFDIS GKAALRQFSG
     HSKAVHFVDF TADKYRIVSG SDDYTSRLWD IPNGVEITSY NEHTDYIRCG CTSALNNDLF
     ATGSYDHTIK IFDGRTDKSV MSMDHGQPVE SVLLFPSGGL LVSAGGRYVK VWDILKGGQL
     LVSLRNHHKT VTSLCLSSSG QRLLSASLDR HVKVYSTMNY KVVHSFDYAA SILSLALAPD
     DQMIVVGMTN GVLNIKHRKP EERKQLQSTT KRHPRYRVFV RGKDYMPKQD DIFISKPVIA
     HLKKYDKLLK GFHMTEALDT VLQPQIRNQR PEVTVAVMNE LKRRGTLKNA LAGRNEKQLS
     DLLIFLLKHL VNPQFVPILL NVAEHIIDIY SPVVGQSSVI YKQFIRLQEV LEKEINYQEE
     LLKMLGMMDT LFATMTTKKE SPWEEPKPIL PLSSQ