ID   UTP16_SCHPO             Reviewed;         327 AA.
AC   O94259;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 2.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Probable U3 small nucleolar RNA-associated protein 16;
DE            Short=U3 snoRNA-associated protein 16;
GN   Name=utp16; ORFNames=SPBP8B7.10c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   REVISION OF GENE MODEL.
RX   PubMed=21511999; DOI=10.1126/science.1203357;
RA   Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA   Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA   Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA   Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA   French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA   Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA   Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA   Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA   Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA   Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT   "Comparative functional genomics of the fission yeasts.";
RL   Science 332:930-936(2011).
RN   [3]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
RN   [4]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-163 AND SER-165, AND
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=18257517; DOI=10.1021/pr7006335;
RA   Wilson-Grady J.T., Villen J., Gygi S.P.;
RT   "Phosphoproteome analysis of fission yeast.";
RL   J. Proteome Res. 7:1088-1097(2008).
CC   -!- FUNCTION: Involved in nucleolar processing of pre-18S ribosomal RNA.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the UTP16 family. {ECO:0000305}.
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DR   EMBL; CU329671; CAA21795.2; -; Genomic_DNA.
DR   PIR; T40804; T40804.
DR   RefSeq; NP_596517.2; NM_001022438.2.
DR   AlphaFoldDB; O94259; -.
DR   SMR; O94259; -.
DR   BioGRID; 277872; 64.
DR   STRING; 4896.SPBP8B7.10c.1; -.
DR   iPTMnet; O94259; -.
DR   MaxQB; O94259; -.
DR   PaxDb; O94259; -.
DR   PRIDE; O94259; -.
DR   EnsemblFungi; SPBP8B7.10c.1; SPBP8B7.10c.1:pep; SPBP8B7.10c.
DR   GeneID; 2541361; -.
DR   KEGG; spo:SPBP8B7.10c; -.
DR   PomBase; SPBP8B7.10c; utp16.
DR   VEuPathDB; FungiDB:SPBP8B7.10c; -.
DR   HOGENOM; CLU_850355_0_0_1; -.
DR   OMA; SQKKRSW; -.
DR   PRO; PR:O94259; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0032040; C:small-subunit processome; ISO:PomBase.
DR   GO; GO:0005732; C:sno(s)RNA-containing ribonucleoprotein complex; ISO:PomBase.
DR   GO; GO:0030515; F:snoRNA binding; ISO:PomBase.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; ISO:PomBase.
DR   InterPro; IPR013268; U3_snoRNA_assoc.
DR   Pfam; PF08297; U3_snoRNA_assoc; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Nucleus; Phosphoprotein; Reference proteome;
KW   Ribonucleoprotein; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..327
FT                   /note="Probable U3 small nucleolar RNA-associated protein
FT                   16"
FT                   /id="PRO_0000343135"
FT   REGION          151..218
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          180..219
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        168..218
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         163
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
FT   MOD_RES         165
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000269|PubMed:18257517"
SQ   SEQUENCE   327 AA;  37808 MW;  FA6DAE457A9A73D0 CRC64;
     MQSSRKIMIL KRNIKGLKSS AIIATYLTLN KLFIDKFCKT QESTYPIHFV HCHFGGIKKF
     HSHCQLSSSY TNSGQKSFKS FNSLRFIVLK SKTCLLRYKL LIKTFCCITY SKIENLSNTR
     MARLTAPSKG PSFSNLNKPN DLLKAEIEDN EASHYSQNQS SDSDSDEAPE EVSLKSSSDE
     VKKRLQRLKG NELQLRKAER EKRRLQNERN RERNAQRVSA SKLDLAILEA AEVEEINSTT
     EIEEKVDEAS LDLYTPKGHK IVFPNNEIPK KRTRSFRKGD FKVSVLKETN DPLLAPNYEK
     KLSQRKRDWI NRQSVPRASK RRRPLTY