ID   UTP25_ARTBC             Reviewed;         717 AA.
AC   D4AUV1;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   18-MAY-2010, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 25;
DE            Short=U3 snoRNA-associated protein 25;
DE   AltName: Full=U three protein 25;
GN   Name=UTP25; ORFNames=ARB_08018;
OS   Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton
OS   mentagrophytes).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=663331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4681 / CBS 112371;
RX   PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA   Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA   Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA   Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA   Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA   Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT   "Comparative and functional genomics provide insights into the
RT   pathogenicity of dermatophytic fungi.";
RL   Genome Biol. 12:R7.1-R7.16(2011).
CC   -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S rRNA
CC       processing, specifically at sites A0, A1, and A2. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC       composed of at least 40 protein subunits and snoRNA U3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UTP25 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ABSU01000011; EFE33266.1; -; Genomic_DNA.
DR   RefSeq; XP_003013906.1; XM_003013860.1.
DR   AlphaFoldDB; D4AUV1; -.
DR   STRING; 663331.D4AUV1; -.
DR   EnsemblFungi; EFE33266; EFE33266; ARB_08018.
DR   GeneID; 9521324; -.
DR   KEGG; abe:ARB_08018; -.
DR   eggNOG; KOG2340; Eukaryota.
DR   HOGENOM; CLU_018705_0_1_1; -.
DR   OMA; KYFRQTI; -.
DR   Proteomes; UP000008866; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010678; UTP25.
DR   PANTHER; PTHR12933; PTHR12933; 1.
DR   Pfam; PF06862; UTP25; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..717
FT                   /note="U3 small nucleolar RNA-associated protein 25"
FT                   /id="PRO_0000408096"
FT   REGION          1..147
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        20..37
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..54
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        56..86
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        89..105
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        121..147
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   717 AA;  81193 MW;  1576099374C88AD6 CRC64;
     MAIQHKKGGG HRGRGSKTGR SRGRKFETSR LKDVREDESS GEEEDVDVQP AEDMNDSEGT
     DVSSESGLDE PPKENSYSTL LKLLNTDAKS NEPARKKRKI KANEPDANLV EVSIPTADDI
     EQMDEVADTE ASASEDENMD DEGLPGEDYA EDIGTDGRND MFELHFGNPD ETELSQKIQA
     CSKAWKSTKA DLIDGLYSVV SMPDVEGNSS AIPEACWSVR LLTYRQLKQK LARNTVSFDR
     LNSCLTPYIF GYHDTFFCSR TTQNSAKLRD LYCLHALNHV LKTRDRVIKN SAILSREDNG
     DVELRDQGFT RPKVLIILPT RQACVRVINS FTKIYPMEQQ ENKKRFMDSF SAADSDEWAH
     KPDDFKELFG GNDDDMFRLG LKFTRKSLKF FSKFYSSDII LASPLGLRTA IEKEGGKKNE
     NDFLSSIEMV IVDHADALIM QNWDHVEYIF SNLNLQPKEA HGCDFSRVRQ WYLDGHGKFL
     RQTLVFSAFN TPELNALYNT QMQNVFGKAK IMSKYEGAML NLRLPISVKQ TFSRFDSASP
     LKDPEARFQY FTRTVLASLA RGWTESSSRK KSGGTLIFIP SYLDFVRVRN HFANSSQTEN
     ISFGLISEYT SVRDSSRARS HFMNGRHSVL LYTERAHHFR RYNIRGVTNI VMYGLPDNPI
     FWGDLIEYLG SAAGGTATPT VRVLFSKWDA LKLERIAGTA RVRSMLLEKG GDTFTFV