ID   UTP25_ASPOR             Reviewed;         724 AA.
AC   Q2UPL9;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 25;
DE            Short=U3 snoRNA-associated protein 25;
DE   AltName: Full=U three protein 25;
GN   Name=utp25; ORFNames=AO090005001591;
OS   Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=510516;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42149 / RIB 40;
RX   PubMed=16372010; DOI=10.1038/nature04300;
RA   Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA   Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA   Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA   Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA   Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA   Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA   Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA   Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA   Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA   Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA   Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA   Kikuchi H.;
RT   "Genome sequencing and analysis of Aspergillus oryzae.";
RL   Nature 438:1157-1161(2005).
CC   -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S rRNA
CC       processing, specifically at sites A0, A1, and A2. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC       composed of at least 40 protein subunits and snoRNA U3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UTP25 family. {ECO:0000305}.
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DR   EMBL; AP007151; BAE56496.1; -; Genomic_DNA.
DR   RefSeq; XP_001818498.1; XM_001818446.1.
DR   AlphaFoldDB; Q2UPL9; -.
DR   STRING; 510516.Q2UPL9; -.
DR   EnsemblFungi; BAE56496; BAE56496; AO090005001591.
DR   GeneID; 5990443; -.
DR   KEGG; aor:AO090005001591; -.
DR   VEuPathDB; FungiDB:AO090005001591; -.
DR   HOGENOM; CLU_018705_0_1_1; -.
DR   OMA; KYFRQTI; -.
DR   Proteomes; UP000006564; Chromosome 1.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010678; UTP25.
DR   PANTHER; PTHR12933; PTHR12933; 1.
DR   Pfam; PF06862; UTP25; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..724
FT                   /note="U3 small nucleolar RNA-associated protein 25"
FT                   /id="PRO_0000408104"
FT   REGION          1..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        37..71
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        95..114
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..164
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   724 AA;  81998 MW;  CF9BDEFF59767E65 CRC64;
     MAPPRNRAPK GRGARARAPI KRRNGFTTSR VDEIESEEPS GGEEGQFEDN LGDEMDYDGP
     MDDASSDSDE DVEDDKSARP YNELLQLLNT TADSKAPARK KRKTEHKDDK RAVAQNDIVV
     AANEEELLED DDLQQQEPSD EEDEDNLDEV DADGQADSDN EDDNDPFEAH FARKEDELSK
     QIKAVGDNKW KTVKKELSED LRLARAAPDT GSDLSCLPAL KSIANLKLKR KLKTPALERL
     SQISGHAQQL APYIFDYQDV LYGARKSSSS TQLRDILAVH AVNHVLKTRD RVLKNNARVA
     KEQDADLDLR DQGFTRPKVL FLLPTKQACV RVVESITQLF QPEQQENKKR FMDTFSATDD
     KSWESKPDDF QELFGGNDDD MFRLGLKFTR KTVKFFAQFY ASDMILASPL GLRTIMDQAD
     AKKRDHDFLS SIEVVIVDQA DALLMQNWDH VDYIFKHLNL QPREAHGCDF SRVRTWYLDN
     NARYVRQMIM LASFITPEIN SVFSTHMLNV SGKIKMTPVY AGAISETPLP VSVKQTFSRF
     DSLSPAKDPD ARFKHFTTTV LSSLVRNVTS GRGNNSGGIL IVIPSYLDFV RVRNYFATSA
     QTMNVSFGAI SEYSDTRDIM RARTHFMNGR HSVLLYTERF HHFRRYQIRG VKRVIMYGVP
     ENPLFWGEIV GFLGMDPAAI DEAAEGGVRA LFSKWDALKL ERIVGTKRVG NMLREKGGDT
     FTFV