ID   UTP25_ASPTN             Reviewed;         723 AA.
AC   Q0CCM6;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 25;
DE            Short=U3 snoRNA-associated protein 25;
DE   AltName: Full=U three protein 25;
GN   Name=utp25; ORFNames=ATEG_08558;
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=341663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA   Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S rRNA
CC       processing, specifically at sites A0, A1, and A2. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC       composed of at least 40 protein subunits and snoRNA U3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UTP25 family. {ECO:0000305}.
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DR   EMBL; CH476606; EAU30690.1; -; Genomic_DNA.
DR   RefSeq; XP_001217144.1; XM_001217143.1.
DR   AlphaFoldDB; Q0CCM6; -.
DR   STRING; 341663.Q0CCM6; -.
DR   EnsemblFungi; EAU30690; EAU30690; ATEG_08558.
DR   GeneID; 4323277; -.
DR   VEuPathDB; FungiDB:ATEG_08558; -.
DR   eggNOG; KOG2340; Eukaryota.
DR   HOGENOM; CLU_018705_0_1_1; -.
DR   OMA; KYFRQTI; -.
DR   OrthoDB; 257318at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010678; UTP25.
DR   PANTHER; PTHR12933; PTHR12933; 1.
DR   Pfam; PF06862; UTP25; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..723
FT                   /note="U3 small nucleolar RNA-associated protein 25"
FT                   /id="PRO_0000408105"
FT   REGION          1..179
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        55..70
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        71..86
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        91..118
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        119..162
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        163..179
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   723 AA;  81404 MW;  3A9AD222CE5D7750 CRC64;
     MAPPRGKGPK RHAKGSRAPV KRKNGFATSR LDEVDSDASS AADEFPTGDL SENEMDHEEA
     GDDASDSEEE DLNAGQSYNE LLQLLQATDS KGPARKKRKV EHKEEKVKKL KTDAVVEGAE
     EEEKEEEEEA VANDLEQQEP SDEEDANLDE ANADEQDSDT EDGTDPFESH FANPKEADLT
     KKIQAVEAKK WTTAKKETEG LRLVRSVPEG AEASFLPTMK SLANVKLKRK LQTTAKDAIP
     SISGHAQHLA PYVFDYQDVL YGARTTSNAV PMRDILAAHA TNHVLKTRDR VLKNNLRAAK
     EQDADLDLRD QGFTRPKVLY LLPSKQACVR VVESITRLFQ PEQQENKKRF LDTFSAEDDV
     SWDNKPDDFR ELFAGNNDDM FRLGLKFTRK TIKFFAQFYT SDMILASPLG LRTIMDQADA
     KKRDHDFLSS IEVVIVDHAD ALQMQNWDHV DYILKHLNLQ PKEAHGCDFS RVRPWYLDNQ
     ARHVRQLIML AGFITPEINS VYSAQMQNVA GKVKATPVYE GAISELPLPV SVKQTFSRFD
     SLSPAKDPDA RFKHFTTTVL STLVRQITAG RGKHRGGVLI VIPSYLDFVR VRNHFATSAQ
     TANLSFGAIS EYTEPREVAR ARSHFMNGRH SVLLYSERFH HFRRYQIRGV RQVVMYGVPE
     NPRFYGEMVG FLGLDAAAVV EAAEGGVRAL FSKWDALKLE RVVGTKRLGN MMRERGGDTF
     TFV