ID   UTP25_BOTFB             Reviewed;         723 AA.
AC   A6RT94;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 25;
DE            Short=U3 snoRNA-associated protein 25;
DE   AltName: Full=U three protein 25;
GN   Name=UTP25; ORFNames=BC1G_03830;
OS   Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis
OS   cinerea).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Botrytis.
OX   NCBI_TaxID=332648;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B05.10;
RX   PubMed=21876677; DOI=10.1371/journal.pgen.1002230;
RA   Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A.,
RA   Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA   Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M.,
RA   Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA   Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA   Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA   Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA   Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C.,
RA   Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA   Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA   Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA   Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA   Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.;
RT   "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT   sclerotiorum and Botrytis cinerea.";
RL   PLoS Genet. 7:E1002230-E1002230(2011).
CC   -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S rRNA
CC       processing, specifically at sites A0, A1, and A2. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC       composed of at least 40 protein subunits and snoRNA U3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UTP25 family. {ECO:0000305}.
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DR   EMBL; CH476855; EDN20635.1; -; Genomic_DNA.
DR   RefSeq; XP_001557733.1; XM_001557683.1.
DR   AlphaFoldDB; A6RT94; -.
DR   PRIDE; A6RT94; -.
DR   GeneID; 5438312; -.
DR   KEGG; bfu:BCIN_04g05800; -.
DR   VEuPathDB; FungiDB:Bcin04g05800; -.
DR   OMA; KYFRQTI; -.
DR   OrthoDB; 257318at2759; -.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010678; UTP25.
DR   PANTHER; PTHR12933; PTHR12933; 1.
DR   Pfam; PF06862; UTP25; 1.
PE   3: Inferred from homology;
KW   Nucleus; Ribonucleoprotein; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..723
FT                   /note="U3 small nucleolar RNA-associated protein 25"
FT                   /id="PRO_0000408106"
FT   REGION          1..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        45..62
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        63..91
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        110..124
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..159
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   723 AA;  81901 MW;  D87E238236DF68B3 CRC64;
     MAFGQRNTSR GGRGGGGGGS SFRGRGGSRG GPRGRGGMRG GRGRGRGRPV FDSARLAQKE
     EDEESDSESE EPSQDEASEE ESSDDDDDDE PVPAVKSYTA LMQSFTRDSA PQAKRRKLNV
     DKEEKEDEDA DLMDEDTNEA DLVEEEEEGP ETATDGILED DEEDKADPFE AHFANPDDNI
     LSRRLQHLEK GQWALRMSSL AKVGTAITSI PGDGEPRAMK AMTIGSPEGL KLKQKLANVI
     KKQRPTFDAL EKSIAPLVFG YQDLLFTERN TSNAESLRRL TCLHAVNHVF KTRDRVIKNN
     SRLAREDSSD DLELRDQGFT RPKVLMLLPT RESCVRMVDM ITSLCEPEQQ ENRKRFNDSF
     VDKEENYSTD KPEDFRELFA GNDDDMFRLG LKFTRKTIKY FSQFYNSDII FASPLGLRMA
     IGDEDAKKVD HDFLSSIEIV IVDQADALLM QNWEHVEFIF DHLNLQPKEA HGCDFSRVRS
     WYLDNNAKYF RQNIALAGFN TPELQTMFYT QSQNWEGKAK VSSTYPGAIQ ELGLKVKQTF
     SRIDTESIAS DPQSRFEYFT SAIIPTLTRR SKDSSGTLLF IPSYMDFVKV RNYFSTSATT
     SSLSFGSISE YTTPKEVARA RSHFFSGRHN VLLYTERAHH FRRYQIRGVK KVIMYGIPEN
     PIFYKEIVAG YLGRSVREGD LEPGNGSLRA VFSKWDSMKL ERIAGTERVN KMIKEKGDTF
     DFL