ID   UTP25_FUSV7             Reviewed;         716 AA.
AC   C7YRJ1;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   13-OCT-2009, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 25;
DE            Short=U3 snoRNA-associated protein 25;
DE   AltName: Full=U three protein 25;
GN   Name=UTP25; ORFNames=NECHADRAFT_61141;
OS   Fusarium vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL
OS   45880 / 77-13-4) (Fusarium solani subsp. pisi).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium solani species complex; Fusarium vanettenii.
OX   NCBI_TaxID=660122;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880 / 77-13-4;
RX   PubMed=19714214; DOI=10.1371/journal.pgen.1000618;
RA   Coleman J.J., Rounsley S.D., Rodriguez-Carres M., Kuo A., Wasmann C.C.,
RA   Grimwood J., Schmutz J., Taga M., White G.J., Zhou S., Schwartz D.C.,
RA   Freitag M., Ma L.-J., Danchin E.G.J., Henrissat B., Coutinho P.M.,
RA   Nelson D.R., Straney D., Napoli C.A., Barker B.M., Gribskov M., Rep M.,
RA   Kroken S., Molnar I., Rensing C., Kennell J.C., Zamora J., Farman M.L.,
RA   Selker E.U., Salamov A., Shapiro H., Pangilinan J., Lindquist E.,
RA   Lamers C., Grigoriev I.V., Geiser D.M., Covert S.F., Temporini E.,
RA   VanEtten H.D.;
RT   "The genome of Nectria haematococca: contribution of supernumerary
RT   chromosomes to gene expansion.";
RL   PLoS Genet. 5:E1000618-E1000618(2009).
CC   -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S rRNA
CC       processing, specifically at sites A0, A1, and A2. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC       composed of at least 40 protein subunits and snoRNA U3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UTP25 family. {ECO:0000305}.
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DR   EMBL; GG698899; EEU45469.1; -; Genomic_DNA.
DR   RefSeq; XP_003051182.1; XM_003051136.1.
DR   AlphaFoldDB; C7YRJ1; -.
DR   STRING; 140110.NechaP61141; -.
DR   EnsemblFungi; NechaT61141; NechaP61141; NechaG61141.
DR   GeneID; 9665890; -.
DR   KEGG; nhe:NECHADRAFT_61141; -.
DR   eggNOG; KOG2340; Eukaryota.
DR   HOGENOM; CLU_018705_0_1_1; -.
DR   InParanoid; C7YRJ1; -.
DR   OMA; KYFRQTI; -.
DR   OrthoDB; 257318at2759; -.
DR   Proteomes; UP000005206; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010678; UTP25.
DR   PANTHER; PTHR12933; PTHR12933; 1.
DR   Pfam; PF06862; UTP25; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..716
FT                   /note="U3 small nucleolar RNA-associated protein 25"
FT                   /id="PRO_0000408123"
FT   REGION          1..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..25
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        50..80
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        97..117
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        118..160
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        161..175
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   716 AA;  81826 MW;  E0F99D35E02F652F CRC64;
     MAPRGRGGNF RGRGGRGRGR GGRGRGRATS RFGPNRRFDG ARLADNDESE SSGSEAESAP
     EDEVMGDVDS DADDDDEDEQ SSKPYMALLQ SFTENNAPKA KRRKLEHQEA QGQPEESSDD
     EKADEEEEEK DIDRAEEDPE DQDAEEQIED DDDSEDEDNL TDPFDTHFAH PDDDTVAKRV
     KAVQKGEWAT KRALIQNLRA TVTYPSSDAG SEVPKPMAGP DGLSLKQKLK ETAARKIGEF
     DAAQRAFSPL LFNYSDVLHC DRTVRNSDSL RKLTCLHALN HVFKTRDRVI KNNYKLAKEG
     QDTELELRDQ GFTRPKVLFL LPTRNSCLRI VNIIRDLCEP DQQENRKRFE EGYVDKEAKF
     GDDRPADFRD LFEGSDDDMF RLGMKFTRKT IKYFSQFYNS DILFASPLGL RMAIGSEEDK
     KLDFDFLSSI EMVVVDQADA LLMQNWEHVE FIFEHLNLQP KDAHGCDFSR VRNWYLEDWA
     KHFRQTVILS AFNTPELSEL LRLHCHNWAG KVRLQPEYPG SLSQLGVKLK QTFSRFRSSS
     VDKDPDARFE YFTSAIVPSL AKRAKDATGT LIFIPSYLDF VRVRNYFATS SAVENVTFGA
     ISEYADVPEA SRARSHFLNG RHRVLLYTER AHHFRRYQLR GVQRVIFYGL PDNPIFYNEI
     AGGYLSKSEQ DMRLEPGQGS VKVVFSKYDV MKLERIVGSK RVGKMIQERG DTFEFI