ID   UTP25_LEPMJ             Reviewed;         741 AA.
AC   E5R5D9;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   08-FEB-2011, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 25;
DE            Short=U3 snoRNA-associated protein 25;
DE   AltName: Full=U three protein 25;
GN   Name=UTP25; ORFNames=Lema_P048150.1;
OS   Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
OS   (Blackleg fungus) (Phoma lingam).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae;
OC   Leptosphaeria; Leptosphaeria maculans species complex.
OX   NCBI_TaxID=985895;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8;
RX   PubMed=21326234; DOI=10.1038/ncomms1189;
RA   Rouxel T., Grandaubert J., Hane J.K., Hoede C., van de Wouw A.P.,
RA   Couloux A., Dominguez V., Anthouard V., Bally P., Bourras S.,
RA   Cozijnsen A.J., Ciuffetti L.M., Degrave A., Dilmaghani A., Duret L.,
RA   Fudal I., Goodwin S.B., Gout L., Glaser N., Linglin J., Kema G.H.J.,
RA   Lapalu N., Lawrence C.B., May K., Meyer M., Ollivier B., Poulain J.,
RA   Schoch C.L., Simon A., Spatafora J.W., Stachowiak A., Turgeon B.G.,
RA   Tyler B.M., Vincent D., Weissenbach J., Amselem J., Quesneville H.,
RA   Oliver R.P., Wincker P., Balesdent M.-H., Howlett B.J.;
RT   "Effector diversification within compartments of the Leptosphaeria maculans
RT   genome affected by Repeat-Induced Point mutations.";
RL   Nat. Commun. 2:202-202(2011).
CC   -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S rRNA
CC       processing, specifically at sites A0, A1, and A2. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC       composed of at least 40 protein subunits and snoRNA U3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UTP25 family. {ECO:0000305}.
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DR   EMBL; FP929083; CBX92109.1; -; Genomic_DNA.
DR   RefSeq; XP_003835474.1; XM_003835426.1.
DR   AlphaFoldDB; E5R5D9; -.
DR   STRING; 985895.E5R5D9; -.
DR   EnsemblFungi; CBX92109; CBX92109; LEMA_P048150.1.
DR   GeneID; 13284123; -.
DR   eggNOG; KOG2340; Eukaryota.
DR   HOGENOM; CLU_018705_0_1_1; -.
DR   InParanoid; E5R5D9; -.
DR   OMA; KYFRQTI; -.
DR   OrthoDB; 257318at2759; -.
DR   Proteomes; UP000002668; Genome.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR010678; UTP25.
DR   PANTHER; PTHR12933; PTHR12933; 1.
DR   Pfam; PF06862; UTP25; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..741
FT                   /note="U3 small nucleolar RNA-associated protein 25"
FT                   /id="PRO_0000408120"
FT   REGION          1..197
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        43..59
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        68..82
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        164..182
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        183..197
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   741 AA;  83853 MW;  385E877BD6112E8A CRC64;
     MAPFRGRGGF RGGARGASMS RGRRGAARGG AKRGGFAAAR TADQVEESNT QFRQAPESEH
     SQPESSDESA SEAEDDEDSE DAQPASAIYA TLLQSMSARK TPFGGTVVDP PHVSHRKKRK
     LHHHVPGPEE VPGAALMPEE GHAHPRGDDQ GSETNGPASG GEDHEEEGEA EDLDEEEEQQ
     RLDNTEDSPF DAHFANPDEN ELAVRLKRIT DNQWITKKLD VGRGRGVLQV PAADEIALSR
     RKVRSTRDVV LKARLVDNAQ KVLGNFDDTE QAIAPSIFDY QDLLFGARTV QNAGRLRDII
     CLHALNHILM TRDRVIKNNA KLAAATDDVD AEYRDQGFTR PKILFLLETK QACVRLLDSI
     TKLHDFEQQE NKKRFLESFS LPEDKFSDEK PADFRELFEG NDENEFRIGV KLTRKTLKLY
     STFYNSDIIL ASALGLRRAI ESGDPKKRDS DFLSSIEMVI MEQADATLMQ NWEHAEFVFE
     HLNLQPKDPH DCDFSRVRSW YLDDQARHIR QTIVLSAYLT PKINTLYNKY MRNVAGRLKY
     TQDYTTGLIE TLSYGIKQTF LRFDSPSHLT DPDARFKYFN TSILPSISRL PKTPEGGPGV
     LVFIPSYLDF VRVRNSLVDS DFSYASISEY TDTTDVRKAR SHFMNGKHSL LLYTGRAHHF
     HRYNIRGVKR VVFYGVPENP RFYDEILGFV GKTVERGEVS RAEAGVRVCF SRWERLELER
     IVGSKRIVRM IADKGDVFDF V