UTP25_PYRTR
ID UTP25_PYRTR Reviewed; 680 AA.
AC B2W0B1;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-2008, sequence version 1.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=U3 small nucleolar RNA-associated protein 25;
DE Short=U3 snoRNA-associated protein 25;
DE AltName: Full=U three protein 25;
GN Name=utp25; ORFNames=PTRG_03896;
OS Pyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot fungus)
OS (Drechslera tritici-repentis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae;
OC Pyrenophora.
OX NCBI_TaxID=426418;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pt-1C-BFP;
RX PubMed=23316438; DOI=10.1534/g3.112.004044;
RA Manning V.A., Pandelova I., Dhillon B., Wilhelm L.J., Goodwin S.B.,
RA Berlin A.M., Figueroa M., Freitag M., Hane J.K., Henrissat B., Holman W.H.,
RA Kodira C.D., Martin J., Oliver R.P., Robbertse B., Schackwitz W.,
RA Schwartz D.C., Spatafora J.W., Turgeon B.G., Yandava C., Young S., Zhou S.,
RA Zeng Q., Grigoriev I.V., Ma L.-J., Ciuffetti L.M.;
RT "Comparative genomics of a plant-pathogenic fungus, Pyrenophora tritici-
RT repentis, reveals transduplication and the impact of repeat elements on
RT pathogenicity and population divergence.";
RL G3 (Bethesda) 3:41-63(2013).
CC -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S rRNA
CC processing, specifically at sites A0, A1, and A2. {ECO:0000250}.
CC -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC composed of at least 40 protein subunits and snoRNA U3. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the UTP25 family. {ECO:0000305}.
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DR EMBL; DS231617; EDU46734.1; -; Genomic_DNA.
DR RefSeq; XP_001934229.1; XM_001934194.1.
DR AlphaFoldDB; B2W0B1; -.
DR STRING; 45151.EDU46734; -.
DR EnsemblFungi; EDU46734; EDU46734; PTRG_03896.
DR GeneID; 6342132; -.
DR eggNOG; KOG2340; Eukaryota.
DR HOGENOM; CLU_018705_0_1_1; -.
DR InParanoid; B2W0B1; -.
DR OMA; KYFRQTI; -.
DR OrthoDB; 257318at2759; -.
DR Proteomes; UP000001471; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0034511; F:U3 snoRNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010678; UTP25.
DR PANTHER; PTHR12933; PTHR12933; 1.
DR Pfam; PF06862; UTP25; 1.
PE 3: Inferred from homology;
KW Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW rRNA processing.
FT CHAIN 1..680
FT /note="U3 small nucleolar RNA-associated protein 25"
FT /id="PRO_0000408136"
FT REGION 1..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 21..40
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..76
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 680 AA; 77605 MW; 7F581E6BB9B7A3B8 CRC64;
MAHVLMVTSN INMREPPETE ESESEASDDA ASDDDEEEAQ PASNAYATLL QSFSTRHAGS
EEHRKKRRKL DHEEVPQEDI SEAEEASVYG TPEGDGTVVD QEQHETDDEA ADEDDGKEQE
LEKAYEKHFA NPDENELATR LKQIAANQWS SQKLTCGSGT TKGFGVLQIP VEEAQTPPKK
LKSVHDIQLK QRLVENAQNK VGNFDQVEQT IAPSIFGYQD LLFGARTVQN ACRLRDITCL
HALNHILMTR DRVLKNNAKL AAAPDDVDAE YRDQGFTRPK ILFLLETKQA CVRVLDSITK
LHEFEQQENK KRFLDSFSQP EDKFSEDRPA DFRELFEGND ENEFRIGVKL TRKTLKLYST
FYNSDIIFAS TLGLRRAIES GDPKKKDYDF LSSIEMVIME QADATLMQNW EHAEYVFEHL
NLQPKDAHGC DFSRVRSWYL DGHAPHIRQT IVLSAFVTPK INTLYNKHMR NVAGRLKYTA
DHTDGLIESL SYGIKQTFVR FDSPSHLTDP DARFKYFSSS ILPSITRLPR TVDAGGLGVL
IFIPSYLDFV RVRNSLVDSD FSYASISEYT DATDVRKARS HFMNGKHALL LYTGRAHHFH
RYNIRGVKRV VFYGVPENPK FYDEVVGFVG KSIERAEISR QEASVRVCFS KWEKMELERI
VGTKRVGKLV RERGDVFDFV