ID   UTP25_SCLS1             Reviewed;         724 AA.
AC   A7EZP8;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 58.
DE   RecName: Full=U3 small nucleolar RNA-associated protein 25;
DE            Short=U3 snoRNA-associated protein 25;
DE   AltName: Full=U three protein 25;
GN   Name=utp25; ORFNames=SS1G_10815;
OS   Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold)
OS   (Whetzelinia sclerotiorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Sclerotinia.
OX   NCBI_TaxID=665079;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18683 / 1980 / Ss-1;
RX   PubMed=21876677; DOI=10.1371/journal.pgen.1002230;
RA   Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A.,
RA   Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA   Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M.,
RA   Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA   Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA   Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA   Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA   Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C.,
RA   Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA   Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA   Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA   Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA   Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.;
RT   "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT   sclerotiorum and Botrytis cinerea.";
RL   PLoS Genet. 7:E1002230-E1002230(2011).
CC   -!- FUNCTION: DEAD-box RNA helicase-like protein required for pre-18S rRNA
CC       processing, specifically at sites A0, A1, and A2. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the ribosomal small subunit (SSU) processome
CC       composed of at least 40 protein subunits and snoRNA U3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UTP25 family. {ECO:0000305}.
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DR   EMBL; CH476636; EDN94940.1; -; Genomic_DNA.
DR   RefSeq; XP_001588368.1; XM_001588318.1.
DR   AlphaFoldDB; A7EZP8; -.
DR   STRING; 665079.A7EZP8; -.
DR   PRIDE; A7EZP8; -.
DR   GeneID; 5484538; -.
DR   KEGG; ssl:SS1G_10815; -.
DR   InParanoid; A7EZP8; -.
DR   OMA; KYFRQTI; -.
DR   Proteomes; UP000001312; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0032040; C:small-subunit processome; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IBA:GO_Central.
DR   GO; GO:0034511; F:U3 snoRNA binding; IBA:GO_Central.
DR   GO; GO:0000462; P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010678; UTP25.
DR   PANTHER; PTHR12933; PTHR12933; 1.
DR   Pfam; PF06862; UTP25; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribonucleoprotein; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..724
FT                   /note="U3 small nucleolar RNA-associated protein 25"
FT                   /id="PRO_0000408139"
FT   REGION          1..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        43..62
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        63..88
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        127..168
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   724 AA;  82103 MW;  330D6813816C849D CRC64;
     MAFGQRNTSR GGRGGGGSSF RGRGGSRGGP RGRGGLRGGR GRGRGRPVFD SARLAQQKEE
     GEESNSESEE SSQDEAMESE EESSDDDDAE PAPAVKSYAA LMQSFTADSA PQAKRRKLNV
     DKEEKQDEEA DLMDQDANDA DHVEEAEEGP ETATDGLLEE EDEEDNSDPF EAHFANPDDN
     ILSRRLKHLE NGQWAIQKSI LAKIGRAITS VPGDDEAKQT KSSIINSPEE LKLKQKLAGV
     MKKQCPTFDT LEKSISPLIF GYQDLLFCER NTSNAESLRR LTCLHAVNHV FKTRDRVIKN
     NSRLAREDNS DDLELRDQGF TRPKVLMLLP TRESCVRMVD MITSLCEPDQ QENRKRFNDS
     YVDKEEKYST DKPEDFRELF AGNDDDMFRL GLKFTRKTVK YFSQFYNSDI IFASPLGLRM
     AIGNEDAKKV DHDFLSSIEM VIVDQADALL MQNWEHVEFI FDHLNLQPKE AHGCDFSRVR
     SWYLDNNAKY FRQTIALAGF NTPELNTMFY NQSKNWAGKV KVSSNYPGAI QELGLKVKQT
     FSRLDSQSFA SDPDSRFEYF TSAIIPTLTR RSKDSAGTLL FIPSYLDFVR VRNYFSTSAT
     TRTLSFGSIS EYTTPKEVAR ARSHFYSGRH TILLYTERAH HFRRYQIRGV KKVIMYGLPD
     NPIFYKEIVG GYLSRSVREG DLEPGDGSVR VVFSKWDVMK LERIAGTERV GKMIKEKGDT
     FDFL