ID   UTS2_GILMI              Reviewed;          12 AA.
AC   P01147;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   07-APR-2021, entry version 53.
DE   RecName: Full=Urotensin-2;
DE   AltName: Full=Urotensin II;
DE            Short=U-II;
DE            Short=UII;
OS   Gillichthys mirabilis (Long-jawed mudsucker).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Gobiaria; Gobiiformes; Gobioidei; Gobiidae; Gobionellinae; Gillichthys.
OX   NCBI_TaxID=8222;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=6107911; DOI=10.1073/pnas.77.8.5021;
RA   Pearson D., Shively J.E., Clark B.R., Geschwind I.I., Barkley M.,
RA   Nishioka R., Bern H.A.;
RT   "Urotensin II: a somatostatin-like peptide in the caudal neurosecretory
RT   system of fishes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 77:5021-5024(1980).
CC   -!- FUNCTION: Urotensin is found in the teleost caudal neurosecretory
CC       system. It has a suggested role in osmoregulation and as a
CC       corticotropin-releasing factor.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the urotensin-2 family. {ECO:0000305}.
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DR   PIR; A01409; UOGM2.
DR   PIR; S42765; S42765.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0097746; P:blood vessel diameter maintenance; IEA:InterPro.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:InterPro.
DR   InterPro; IPR001483; Urotensin_II.
DR   Pfam; PF02083; Urotensin_II; 1.
DR   PROSITE; PS00984; UROTENSIN_II; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Hormone; Secreted.
FT   PEPTIDE         1..12
FT                   /note="Urotensin-2"
FT                   /id="PRO_0000044568"
FT   DISULFID        6..11
FT                   /evidence="ECO:0000269|PubMed:6107911"
SQ   SEQUENCE   12 AA;  1364 MW;  968BF8982679CEBA CRC64;
     AGTADCFWKY CV