ID   UTS2_SCYCA              Reviewed;          12 AA.
AC   P35490;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   07-APR-2021, entry version 49.
DE   RecName: Full=Urotensin-2;
DE   AltName: Full=Urotensin II;
DE            Short=U-II;
DE            Short=UII;
OS   Scyliorhinus canicula (Small-spotted catshark) (Squalus canicula).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC   Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC   Scyliorhinus.
OX   NCBI_TaxID=7830;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Spinal cord;
RX   PubMed=1620290; DOI=10.1159/000126119;
RA   Conlon J.M., O'Harte F., Smith D.D., Balment R.J., Hazon N.;
RT   "Purification and characterization of urotensin II and parvalbumin from an
RT   elasmobranch fish, Scyliorhinus canicula (common dogfish).";
RL   Neuroendocrinology 55:230-235(1992).
CC   -!- FUNCTION: Has a suggested role in osmoregulation and as a
CC       corticotropin-releasing factor. Probably involved in smooth muscle
CC       stimulation.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the urotensin-2 family. {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   GO; GO:0097746; P:blood vessel diameter maintenance; IEA:InterPro.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:InterPro.
DR   InterPro; IPR001483; Urotensin_II.
DR   Pfam; PF02083; Urotensin_II; 1.
DR   PROSITE; PS00984; UROTENSIN_II; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Hormone; Secreted.
FT   PEPTIDE         1..12
FT                   /note="Urotensin-2"
FT                   /id="PRO_0000044570"
FT   DISULFID        6..11
SQ   SEQUENCE   12 AA;  1526 MW;  804729F9D579CEBA CRC64;
     NNFSDCFWKY CV