ID   UVE1H_MIMIV             Reviewed;         330 AA.
AC   Q5UNU2;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   29-SEP-2021, entry version 69.
DE   RecName: Full=Putative UV-damage endonuclease;
DE            EC=3.-.-.-;
GN   OrderedLocusNames=MIMI_L687;
OS   Acanthamoeba polyphaga mimivirus (APMV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Megaviricetes;
OC   Imitervirales; Mimiviridae; Mimivirus.
OX   NCBI_TaxID=212035;
OH   NCBI_TaxID=5757; Acanthamoeba polyphaga (Amoeba).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Rowbotham-Bradford;
RX   PubMed=15486256; DOI=10.1126/science.1101485;
RA   Raoult D., Audic S., Robert C., Abergel C., Renesto P., Ogata H.,
RA   La Scola B., Susan M., Claverie J.-M.;
RT   "The 1.2-megabase genome sequence of Mimivirus.";
RL   Science 306:1344-1350(2004).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], AND SUBCELLULAR
RP   LOCATION.
RX   PubMed=16971431; DOI=10.1128/jvi.00940-06;
RA   Renesto P., Abergel C., Decloquement P., Moinier D., Azza S., Ogata H.,
RA   Fourquet P., Gorvel J.-P., Claverie J.-M., Raoult D.;
RT   "Mimivirus giant particles incorporate a large fraction of anonymous and
RT   unique gene products.";
RL   J. Virol. 80:11678-11685(2006).
CC   -!- FUNCTION: Endonuclease for the repair of UV-irradiated DNA.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:16971431}.
CC   -!- SIMILARITY: Belongs to the uve1/UvsE family. {ECO:0000305}.
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DR   EMBL; AY653733; AAV50948.1; -; Genomic_DNA.
DR   RefSeq; YP_003987214.1; NC_014649.1.
DR   SMR; Q5UNU2; -.
DR   GeneID; 9925338; -.
DR   KEGG; vg:9925338; -.
DR   Proteomes; UP000001134; Genome.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   GO; GO:0009411; P:response to UV; IEA:InterPro.
DR   InterPro; IPR004601; UvdE.
DR   InterPro; IPR036237; Xyl_isomerase-like_sf.
DR   PANTHER; PTHR31290; PTHR31290; 1.
DR   Pfam; PF03851; UvdE; 1.
DR   SUPFAM; SSF51658; SSF51658; 1.
DR   TIGRFAMs; TIGR00629; uvde; 1.
PE   1: Evidence at protein level;
KW   DNA damage; DNA excision; DNA repair; Endonuclease; Hydrolase; Nuclease;
KW   Reference proteome; Virion.
FT   CHAIN           1..330
FT                   /note="Putative UV-damage endonuclease"
FT                   /id="PRO_0000309193"
SQ   SEQUENCE   330 AA;  38547 MW;  4AAE4764E2C67212 CRC64;
     MNQNLIRLGY ACLNSDLRNY DIFTSRKPIL KTVKSQGFDY VKETIIRNLR DLFTIIIYNE
     SHGIRFFRIS SSIFPHLGNP LLPDSDYDLS FAKNLIKEIG SYAKINGHRL TMHPGQFVQL
     GSNNEEVVRR SFVELQNHAT LLEMLGYSSL DSSVLIVHGG GTFGDKETTL ERWKSNFRKL
     PENIRQLICL ENDENSYGIL DLLPVCEELN VPFCLDIFHN RVSKNRIPLT KKLMKRIINT
     WKRRNMTPKM HFSNQEPGLR RGAHSKTINE LPEYLFRIPD MFQTSLDIIL EVKDKEKSVL
     KMYFKYFDIE TNIDGRNNFI LKKDYSLKKN