ID   UVP1_ECOLX              Reviewed;         198 AA.
AC   P18957;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Protein uvp1;
GN   Name=uvp1;
OS   Escherichia coli.
OG   Plasmid pR.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2550763; DOI=10.1007/bf00330560;
RA   Gigliani F., Sporeno E., Perri S., Battaglia P.A.;
RT   "The uvp1 gene of plasmid pR cooperates with mucAB genes in the DNA repair
RT   process.";
RL   Mol. Gen. Genet. 218:18-24(1989).
CC   -!- FUNCTION: Cooperates with the mucAB genes in the DNA repair process.
CC       Could be a resolvase-invertase protein.
CC   -!- SIMILARITY: Belongs to the site-specific recombinase resolvase family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X16119; CAA34249.1; -; Genomic_DNA.
DR   PIR; S04903; S04903.
DR   AlphaFoldDB; P18957; -.
DR   SMR; P18957; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000150; F:DNA strand exchange activity; IEA:UniProtKB-KW.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1390; -; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006118; Recombinase_CS.
DR   InterPro; IPR006119; Resolv_N.
DR   InterPro; IPR036162; Resolvase-like_N_sf.
DR   InterPro; IPR006120; Resolvase_HTH_dom.
DR   Pfam; PF02796; HTH_7; 1.
DR   Pfam; PF00239; Resolvase; 1.
DR   SMART; SM00857; Resolvase; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF53041; SSF53041; 1.
DR   PROSITE; PS00398; RECOMBINASES_2; 1.
DR   PROSITE; PS51736; RECOMBINASES_3; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA integration; DNA invertase; DNA recombination; DNA repair;
KW   DNA-binding; Plasmid.
FT   CHAIN           1..198
FT                   /note="Protein uvp1"
FT                   /id="PRO_0000196385"
FT   DOMAIN          1..140
FT                   /note="Resolvase/invertase-type recombinase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
FT   DNA_BIND        168..187
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        9
FT                   /note="O-(5'-phospho-DNA)-serine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
SQ   SEQUENCE   198 AA;  22127 MW;  8011E7678E7B0548 CRC64;
     MIIGYARKST HLQDVTHQVD ELTKAGCEQI YHEQISRGGS KRAKNGAPEL ENCLKALREG
     DTLVVWALDR LGGSLSQVIT LLDDLKKRGI TFIAIKDRID TSAPVIGEIY THLMAIFSNF
     ERNRNIERTR SGLAAARARG RVGGRKPSLS EDDINEMKIL LADPEMTVGA VAKRFNVSRM
     TIYRYTTKGN HSEKINDE