ID   UVRA_PARDE              Reviewed;         110 AA.
AC   P29927;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=UvrABC system protein A;
DE            Short=UvrA protein;
DE   AltName: Full=Excinuclease ABC subunit A;
DE   Flags: Fragment;
GN   Name=uvrA;
OS   Paracoccus denitrificans.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Paracoccus.
OX   NCBI_TaxID=266;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 13543 / NRRL B-3784 / NRC 449;
RX   PubMed=1637825; DOI=10.1021/bi00145a009;
RA   Xu X., Matsuno-Yagi A., Yagi T.;
RT   "Gene cluster of the energy-transducing NADH-quinone oxidoreductase of
RT   Paracoccus denitrificans: characterization of four structural gene
RT   products.";
RL   Biochemistry 31:6925-6932(1992).
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein.
CC       A damage recognition complex composed of 2 UvrA and 2 UvrB subunits
CC       scans DNA for abnormalities. When the presence of a lesion has been
CC       verified by UvrB, the UvrA molecules dissociate (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Forms a heterotetramer with UvrB during the search for
CC       lesions. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC       {ECO:0000305}.
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DR   EMBL; M93015; AAA03034.1; -; Unassigned_DNA.
DR   PIR; A42573; A42573.
DR   AlphaFoldDB; P29927; -.
DR   SMR; P29927; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; DNA damage; DNA excision; DNA repair; DNA-binding;
KW   Excision nuclease; Nucleotide-binding; Repeat; SOS response.
FT   CHAIN           <1..110
FT                   /note="UvrABC system protein A"
FT                   /id="PRO_0000093075"
FT   NON_TER         1
SQ   SEQUENCE   110 AA;  11786 MW;  4335B7539C65B964 CRC64;
     KLSKELSRRA TGKTLYILDE PTTGLHFEDV RKLLEVLHSL VDQGNTVVVI EHNLDVIKTA
     DWIIDIGPEG GDGGGAIVAT GTPEQVAEVP ESHTGRYLAP MLDAARSAAE