ID   CAF17_COCIM             Reviewed;         425 AA.
AC   Q1DK38; A0A0D6K9M4; J3K2T4;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Putative transferase CAF17, mitochondrial;
DE            EC=2.1.-.-;
DE   Flags: Precursor;
GN   Name=CAF17; ORFNames=CIMG_09325;
OS   Coccidioides immitis (strain RS) (Valley fever fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=246410;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RS;
RX   PubMed=19717792; DOI=10.1101/gr.087551.108;
RA   Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA   Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA   McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA   Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA   Henn M.R., Birren B.W., Taylor J.W.;
RT   "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT   and their relatives.";
RL   Genome Res. 19:1722-1731(2009).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=RS;
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GcvT family. CAF17 subfamily. {ECO:0000305}.
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DR   EMBL; GG704915; EAS28121.1; -; Genomic_DNA.
DR   RefSeq; XP_001239704.1; XM_001239703.1.
DR   AlphaFoldDB; Q1DK38; -.
DR   SMR; Q1DK38; -.
DR   STRING; 246410.Q1DK38; -.
DR   EnsemblFungi; EAS28121; EAS28121; CIMG_09325.
DR   GeneID; 4559074; -.
DR   KEGG; cim:CIMG_09325; -.
DR   VEuPathDB; FungiDB:CIMG_09325; -.
DR   InParanoid; Q1DK38; -.
DR   OMA; LCRLEVM; -.
DR   OrthoDB; 1342242at2759; -.
DR   Proteomes; UP000001261; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1360.120; -; 1.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   InterPro; IPR045179; YgfZ/GcvT.
DR   InterPro; IPR017703; YgfZ/GcvT_CS.
DR   PANTHER; PTHR22602; PTHR22602; 1.
DR   TIGRFAMs; TIGR03317; ygfZ_signature; 1.
PE   3: Inferred from homology;
KW   Mitochondrion; Reference proteome; Transferase; Transit peptide.
FT   TRANSIT         1..28
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..425
FT                   /note="Putative transferase CAF17, mitochondrial"
FT                   /id="PRO_0000301697"
FT   REGION          403..425
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   425 AA;  46773 MW;  82B8C93C3692D2D6 CRC64;
     MPPRLRPGSV CSRCHFHRRS LSSTAFLAQK QAERPPPPPE AGHVRLVNRA LISLTGADST
     SFLQGLITQN VVSAKSRASP TTPFYAGFLN AQGRLLHDTF IYPTLPEENG GNEGMELGYL
     IEVDKEQVTN LLKHLKKHKL RAKLKFRALD EGERGVWAVW DNAKNWETKD TGDVLREVIT
     CADNRAPAFG YRVLLAGDNL QNLSQPLPGQ QASLSTYTLR RILHGIPEGQ DELGRESALP
     MDSNMDIMGG IDFHKGCYLG QELTIRTHHR GVVRKRVLPV QLYNTEDPKP MPSSSGIPVY
     SPDSQLLLPS AGANITKSSA SGKGRSAGKF ISRIGNVGLA LCRLETMTDI SLTGESSQYN
     PSEEFKISWE ANADAGVAEA GEVKVTAFIP PWVKDYILHG GTRQRQTKED VHRAKSGTEQ
     IEEED