ID   UVRC_CHESB              Reviewed;         653 AA.
AC   Q11GV7;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203};
DE            Short=Protein UvrC {ECO:0000255|HAMAP-Rule:MF_00203};
DE   AltName: Full=Excinuclease ABC subunit C {ECO:0000255|HAMAP-Rule:MF_00203};
GN   Name=uvrC {ECO:0000255|HAMAP-Rule:MF_00203}; OrderedLocusNames=Meso_1975;
OS   Chelativorans sp. (strain BNC1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Phyllobacteriaceae; Chelativorans; unclassified Chelativorans.
OX   NCBI_TaxID=266779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BNC1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.;
RT   "Complete sequence of chromosome of Mesorhizobium sp. BNC1.";
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrC both incises the 5' and 3' sides of the
CC       lesion. The N-terminal half is responsible for the 3' incision and the
CC       C-terminal half is responsible for the 5' incision. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
CC   -!- SUBUNIT: Interacts with UvrB in an incision complex.
CC       {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SIMILARITY: Belongs to the UvrC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
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DR   EMBL; CP000390; ABG63368.1; -; Genomic_DNA.
DR   RefSeq; WP_011581310.1; NC_008254.1.
DR   AlphaFoldDB; Q11GV7; -.
DR   SMR; Q11GV7; -.
DR   STRING; 266779.Meso_1975; -.
DR   PRIDE; Q11GV7; -.
DR   EnsemblBacteria; ABG63368; ABG63368; Meso_1975.
DR   KEGG; mes:Meso_1975; -.
DR   eggNOG; COG0322; Bacteria.
DR   HOGENOM; CLU_014841_3_0_5; -.
DR   OMA; HIECFDN; -.
DR   OrthoDB; 1036075at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009381; F:excinuclease ABC activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.340; -; 1.
DR   Gene3D; 3.40.1440.10; -; 1.
DR   HAMAP; MF_00203; UvrC; 1.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR001943; UVR_dom.
DR   InterPro; IPR036876; UVR_dom_sf.
DR   InterPro; IPR004791; UvrC.
DR   InterPro; IPR001162; UvrC_RNase_H_dom.
DR   InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF02151; UVR; 1.
DR   Pfam; PF08459; UvrC_HhH_N; 1.
DR   SMART; SM00465; GIYc; 1.
DR   SMART; SM00278; HhH1; 2.
DR   SUPFAM; SSF46600; SSF46600; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   TIGRFAMs; TIGR00194; uvrC; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
DR   PROSITE; PS50151; UVR; 1.
DR   PROSITE; PS50165; UVRC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA excision; DNA repair; Excision nuclease;
KW   SOS response.
FT   CHAIN           1..653
FT                   /note="UvrABC system protein C"
FT                   /id="PRO_0000264910"
FT   DOMAIN          44..122
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   DOMAIN          232..267
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
SQ   SEQUENCE   653 AA;  72244 MW;  0486AFBC1CF43861 CRC64;
     MNAADLGNTI ISAEDSTLEW DRAGTETAAT GVEVIQAVVK RLPNAPGVYR MVNTEGDVLY
     VGKARSLKKR VTNYAQGRGH SNRIERMIRE TATMEFVVTR TETEALLLEA NLIKRLRPRF
     NVLMRDDKSF PYILLTGNHP APGIFKHRGA RSRRGDYFGP FASAGAVGRT INSLQRAFLL
     RTCTDSVFES RTRPCLLYQI KRCSGPCTRE ISVEDYATLV KEAKDFLSGR SSTVKAEIAT
     AMQEASQALD FERAAIYRDR LAALSHVQSH QGINPQGLEE ADVFAIHQEG GQTCIQVFFF
     RTGQNWGNRA YFPKADPALG HGEVLGSFLA QFYDDKPCPR LILLSHPVED QDLLAEALSA
     RAGRKVQVSV PARGEKKDLT DHALQNAREA LGRRLAETSS QARLLEGLAE TFGLEAAPRR
     IEVYDNSHIM GTNAVGAMIV AGPEGFVKNQ YRKFNIRSAE ITPGDDFGMM REVMQRRFAR
     LIKEQGLPGN GSEAEDSDAS FPAWPDLILI DGGQGQMSAV RQILDDLGIA DLVTAIGVAK
     GVDRDAGRER FFMEGRPPFT LPPRDPVLYF VQRLRDEAHR FAIGSHRARR KKEMVKNPLD
     EIAGIGPGRK RALLHHFGTA KAVSRAAVED LMEVGGISES IARLIYNHFH ESG