ID   UVRC_CHLCH              Reviewed;         629 AA.
AC   Q3AQX4;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203};
DE            Short=Protein UvrC {ECO:0000255|HAMAP-Rule:MF_00203};
DE   AltName: Full=Excinuclease ABC subunit C {ECO:0000255|HAMAP-Rule:MF_00203};
GN   Name=uvrC {ECO:0000255|HAMAP-Rule:MF_00203}; OrderedLocusNames=Cag_1341;
OS   Chlorobium chlorochromatii (strain CaD3).
OC   Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC   Chlorobium/Pelodictyon group; Chlorobium.
OX   NCBI_TaxID=340177;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CaD3;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Bryant D., Schmutz J., Larimer F.,
RA   Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Chlorobium chlorochromatii CaD3.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrC both incises the 5' and 3' sides of the
CC       lesion. The N-terminal half is responsible for the 3' incision and the
CC       C-terminal half is responsible for the 5' incision. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
CC   -!- SUBUNIT: Interacts with UvrB in an incision complex.
CC       {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SIMILARITY: Belongs to the UvrC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
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DR   EMBL; CP000108; ABB28601.1; -; Genomic_DNA.
DR   RefSeq; WP_011362365.1; NC_007514.1.
DR   AlphaFoldDB; Q3AQX4; -.
DR   SMR; Q3AQX4; -.
DR   STRING; 340177.Cag_1341; -.
DR   EnsemblBacteria; ABB28601; ABB28601; Cag_1341.
DR   KEGG; cch:Cag_1341; -.
DR   eggNOG; COG0322; Bacteria.
DR   HOGENOM; CLU_014841_3_2_10; -.
DR   OMA; HIECFDN; -.
DR   OrthoDB; 1036075at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009381; F:excinuclease ABC activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.340; -; 1.
DR   Gene3D; 3.40.1440.10; -; 1.
DR   HAMAP; MF_00203; UvrC; 1.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR001943; UVR_dom.
DR   InterPro; IPR036876; UVR_dom_sf.
DR   InterPro; IPR004791; UvrC.
DR   InterPro; IPR001162; UvrC_RNase_H_dom.
DR   InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF02151; UVR; 1.
DR   Pfam; PF08459; UvrC_HhH_N; 1.
DR   SMART; SM00465; GIYc; 1.
DR   SUPFAM; SSF46600; SSF46600; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   TIGRFAMs; TIGR00194; uvrC; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
DR   PROSITE; PS50151; UVR; 1.
DR   PROSITE; PS50165; UVRC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA excision; DNA repair; Excision nuclease;
KW   SOS response.
FT   CHAIN           1..629
FT                   /note="UvrABC system protein C"
FT                   /id="PRO_0000227414"
FT   DOMAIN          26..105
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   DOMAIN          219..254
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
SQ   SEQUENCE   629 AA;  71273 MW;  56672D402E5A5560 CRC64;
     MEPLDALEKH GDIKKVLTEK LATLPTSPGI YQFKNSAGRI IYVGKAKNLR NRVRSYFRNS
     HQLFGKTLVL VSHIDDLEVI ITSSEVEALI LENNLIKELK PRYNVNLKDD KTYPYLVITN
     EPYPRILFTR HRRNDGSIAF GPYTEARQLR SILDLIGSIF PVRSCKLRLT PDAIASGKYK
     VCLDYHIHKC KGACEGLQPE DEYRQMIDEI IKLLKGKTSA LIRSLTENMH LAATELRFEQ
     AAEIKAQIES LKRYAERQKV VAADMVDRDV FAIAAGEDDA CGVIFKIREG KLLGSQRIYI
     NNTNGESEAS MQLRMLEKFY VESIEPVPDE ILLQEALSEE EEETLRAFLL VKAKNEGQEK
     KGIRLVVPQI GDKAHLVGMC RQNARHHLEE YLIQKQKRGE AAREHFGLTA LKELLHLPTL
     PQRIECFDNS HFQGTDYVSS MVCFEKGKTK KSDYRKFKIK TFEGSDDYAA MDEVLRRRYS
     GSLTESLALP DLIVVDGGKG QVNTAYKTLQ ELGVTIPVIG LAKRIEEIFT PHSSDPFNLP
     KTSPALKLLQ QLRDEAHRFA ITYHRKLRSD RTLQTELTTI AGIGEKTAFK LLEHFGSVES
     VAQASREELQ AVIGAKAGET VYTFYRPEG