CAF1M_ARATH
ID CAF1M_ARATH Reviewed; 405 AA.
AC Q8VYD9; O65549; Q94B45;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=CRS2-associated factor 1, mitochondrial;
DE Flags: Precursor;
GN OrderedLocusNames=At4g31010; ORFNames=F6I18.80;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: May be involved in the splicing of group IIB introns in
CC mitochondria. {ECO:0000250}.
CC -!- SUBUNIT: Part of large ribonucleo-protein complexes that include group
CC IIB introns. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q8VYD9-1; Sequence=Displayed;
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA18192.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB79819.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL022198; CAA18192.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161578; CAB79819.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE85846.1; -; Genomic_DNA.
DR EMBL; AY042864; AAK68804.1; -; mRNA.
DR EMBL; AY072146; AAL59968.1; -; mRNA.
DR EMBL; AY096489; AAM20129.1; -; mRNA.
DR PIR; B85363; B85363.
DR RefSeq; NP_194830.2; NM_119251.5. [Q8VYD9-1]
DR AlphaFoldDB; Q8VYD9; -.
DR SMR; Q8VYD9; -.
DR STRING; 3702.AT4G31010.1; -.
DR PaxDb; Q8VYD9; -.
DR PRIDE; Q8VYD9; -.
DR ProteomicsDB; 239090; -. [Q8VYD9-1]
DR EnsemblPlants; AT4G31010.1; AT4G31010.1; AT4G31010. [Q8VYD9-1]
DR GeneID; 829228; -.
DR Gramene; AT4G31010.1; AT4G31010.1; AT4G31010. [Q8VYD9-1]
DR KEGG; ath:AT4G31010; -.
DR Araport; AT4G31010; -.
DR TAIR; locus:2126694; AT4G31010.
DR eggNOG; ENOG502QQI8; Eukaryota.
DR HOGENOM; CLU_053415_1_0_1; -.
DR InParanoid; Q8VYD9; -.
DR PhylomeDB; Q8VYD9; -.
DR PRO; PR:Q8VYD9; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q8VYD9; baseline and differential.
DR Genevisible; Q8VYD9; AT.
DR GO; GO:0005739; C:mitochondrion; IDA:TAIR.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR GO; GO:0000373; P:Group II intron splicing; IMP:TAIR.
DR GO; GO:0033617; P:mitochondrial cytochrome c oxidase assembly; IMP:TAIR.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IMP:TAIR.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.30.110.60; -; 2.
DR InterPro; IPR044599; CAF1P_plant.
DR InterPro; IPR001890; RNA-binding_CRM.
DR InterPro; IPR035920; YhbY-like_sf.
DR PANTHER; PTHR46247; PTHR46247; 1.
DR Pfam; PF01985; CRS1_YhbY; 2.
DR SMART; SM01103; CRS1_YhbY; 2.
DR SUPFAM; SSF75471; SSF75471; 2.
DR PROSITE; PS51295; CRM; 2.
PE 2: Evidence at transcript level;
KW Alternative splicing; Mitochondrion; mRNA processing; mRNA splicing;
KW Reference proteome; Repeat; Ribonucleoprotein; RNA-binding;
KW Transit peptide.
FT TRANSIT 1..20
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 21..405
FT /note="CRS2-associated factor 1, mitochondrial"
FT /id="PRO_0000283617"
FT DOMAIN 157..255
FT /note="CRM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00626"
FT DOMAIN 277..373
FT /note="CRM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00626"
FT REGION 32..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 384..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 405 AA; 46393 MW; 3FA634C2EF616146 CRC64;
MFLIRLSRHN PSSFTLLTRR LHDQTISSSR LRDLYNFQSP PPLSSSASEN PDFNQKNNNK
KKPKPQYRPP SSLEGVKTVH SDLPFDFRFS YTESCSNVRP IGLREPKYSP FGPDRLDREW
TGVCAPAVNP KVESVDGVED PKLEEKRRKV REKIQGASLT EAERKFLVEL CQRNKTKRQV
NLGRDGLTHN MLNDVYNHWK HAEAVRVKCL GVPTLDMKNV IFHLEDKTFG QVVSKHSGTL
VLYRGRNYDP KKRPKIPLML WKPHEPVYPR LIKTTIDGLS IDETKAMRKK GLAVPALTKL
AKNGYYGSLV PMVRDAFLVS ELVRIDCLGL ERKDYKKIGA KLRDLVPCIL VTFDKEQVVI
WRGKDYKPPK EDDEYSSFIH RESSIDSDVD LSCSRGAQDS PDETT
