ID   UVRC_MYCAP              Reviewed;         571 AA.
AC   O84899; A5IYU1;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 109.
DE   RecName: Full=UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203};
DE            Short=Protein UvrC {ECO:0000255|HAMAP-Rule:MF_00203};
DE   AltName: Full=Excinuclease ABC subunit C {ECO:0000255|HAMAP-Rule:MF_00203};
GN   Name=uvrC {ECO:0000255|HAMAP-Rule:MF_00203}; OrderedLocusNames=MAG5020;
OS   Mycoplasmopsis agalactiae (strain NCTC 10123 / CIP 59.7 / PG2) (Mycoplasma
OS   agalactiae).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasmopsis.
OX   NCBI_TaxID=347257;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=9664578; DOI=10.1006/mcpr.1998.0160;
RA   Subramaniam S., Bergonier D., Poumarat F., Capaul S., Schlatter Y.,
RA   Nicolet J., Frey J.;
RT   "Species identification of Mycoplasma bovis and Mycoplasma agalactiae based
RT   on the uvrC genes by PCR.";
RL   Mol. Cell. Probes 12:161-169(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 10123 / CIP 59.7 / PG2;
RX   PubMed=17511520; DOI=10.1371/journal.pgen.0030075;
RA   Sirand-Pugnet P., Lartigue C., Marenda M., Jacob D., Barre A., Barbe V.,
RA   Schenowitz C., Mangenot S., Couloux A., Segurens B., de Daruvar A.,
RA   Blanchard A., Citti C.;
RT   "Being pathogenic, plastic, and sexual while living with a nearly minimal
RT   bacterial genome.";
RL   PLoS Genet. 3:744-758(2007).
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrC both incises the 5' and 3' sides of the
CC       lesion. The N-terminal half is responsible for the 3' incision and the
CC       C-terminal half is responsible for the 5' incision. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
CC   -!- SUBUNIT: Interacts with UvrB in an incision complex.
CC       {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SIMILARITY: Belongs to the UvrC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
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DR   EMBL; AF003960; AAC32310.1; -; Genomic_DNA.
DR   EMBL; CU179680; CAL59200.1; -; Genomic_DNA.
DR   RefSeq; WP_011949668.1; NC_009497.1.
DR   AlphaFoldDB; O84899; -.
DR   SMR; O84899; -.
DR   STRING; 347257.MAG5020; -.
DR   EnsemblBacteria; CAL59200; CAL59200; MAG5020.
DR   KEGG; maa:MAG5020; -.
DR   HOGENOM; CLU_014841_3_2_14; -.
DR   OMA; HIECFDN; -.
DR   Proteomes; UP000007065; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009381; F:excinuclease ABC activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.340; -; 1.
DR   Gene3D; 3.40.1440.10; -; 1.
DR   HAMAP; MF_00203; UvrC; 1.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR001943; UVR_dom.
DR   InterPro; IPR036876; UVR_dom_sf.
DR   InterPro; IPR004791; UvrC.
DR   InterPro; IPR001162; UvrC_RNase_H_dom.
DR   InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF02151; UVR; 1.
DR   Pfam; PF08459; UvrC_HhH_N; 1.
DR   SMART; SM00465; GIYc; 1.
DR   SUPFAM; SSF46600; SSF46600; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
DR   PROSITE; PS50151; UVR; 1.
DR   PROSITE; PS50165; UVRC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA excision; DNA repair; Excision nuclease;
KW   Reference proteome; SOS response.
FT   CHAIN           1..571
FT                   /note="UvrABC system protein C"
FT                   /id="PRO_0000138315"
FT   DOMAIN          15..93
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   DOMAIN          184..219
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
SQ   SEQUENCE   571 AA;  66215 MW;  74403690A5FE203C CRC64;
     MDKNEIILKL KNTSTSPGVY LWKDAKQNVL YVGKAKNLRK RLLQYFDGAI NSYKTSKLMS
     LVADFEVYIC KTNKEALLLE KAMVDRFNPE FNILLLDDRK YPYLKVQLLK DSLLITLSRK
     VNTKYTKNTL YYGPFPSGYG AKPILKLLQH EALYESGLLI KNNDSSFWVN QFAKIKEILS
     FKNNNYLNEL TNKMHTAANN MQFELALFLR DGLTYLKKLK ESQIIELSQY KNIDVFAYKT
     DEKLIYATVL FYRYGVLINK VNLTIPLGIS IDESIRVFFE QFYADKILPD NFIVQEEILK
     YDLNLSSDYK FISPKIGTNK KVLDLALLNL NDYYEKEHLI MQNQLEKADS MLSSLNKYLN
     LPKLKNIVIF DNSNINNINP VGVAIVYTNG IKNKSLYRKF NLEALSYRSA DVDYIRQSIT
     KFFSSDKNTK DFDLIITDGG LQQVNEAKKT LKVLGINIPV IGLVKNEYHK TRALIDLNLN
     EIYVNDLELH NYLAQIQIEV DRFAKSHFRN RQKISSLEGK LRNIKGLGHN MEQKLLNHFK
     SYAKIYDASV EELAKIVPFN VAKSIKNKDY E