ID   UVRC_MYCBG              Reviewed;         571 AA.
AC   O84898; E4PZM9;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 120.
DE   RecName: Full=UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203};
DE            Short=Protein UvrC {ECO:0000255|HAMAP-Rule:MF_00203};
DE   AltName: Full=Excinuclease ABC subunit C {ECO:0000255|HAMAP-Rule:MF_00203};
GN   Name=uvrC {ECO:0000255|HAMAP-Rule:MF_00203};
GN   OrderedLocusNames=MBOVPG45_0314;
OS   Mycoplasmopsis bovis (strain ATCC 25523 / DSM 22781 / NCTC 10131 / PG45)
OS   (Mycoplasma bovis).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasmopsis.
OX   NCBI_TaxID=289397;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 25523 / DSM 22781 / NCTC 10131 / PG45;
RX   PubMed=9664578; DOI=10.1006/mcpr.1998.0160;
RA   Subramaniam S., Bergonier D., Poumarat F., Capaul S., Schlatter Y.,
RA   Nicolet J., Frey J.;
RT   "Species identification of Mycoplasma bovis and Mycoplasma agalactiae based
RT   on the uvrC genes by PCR.";
RL   Mol. Cell. Probes 12:161-169(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25523 / DSM 22781 / NCTC 10131 / PG45;
RX   PubMed=21134966; DOI=10.1128/iai.00726-10;
RA   Wise K.S., Calcutt M.J., Foecking M.F., Roske K., Madupu R., Methe B.A.;
RT   "Complete genome sequence of Mycoplasma bovis type strain PG45 (ATCC
RT   25523).";
RL   Infect. Immun. 79:982-983(2011).
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrC both incises the 5' and 3' sides of the
CC       lesion. The N-terminal half is responsible for the 3' incision and the
CC       C-terminal half is responsible for the 5' incision. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
CC   -!- SUBUNIT: Interacts with UvrB in an incision complex.
CC       {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SIMILARITY: Belongs to the UvrC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
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DR   EMBL; AF003959; AAC32309.1; -; Genomic_DNA.
DR   EMBL; CP002188; ADR25362.1; -; Genomic_DNA.
DR   RefSeq; WP_013456570.1; NC_014760.1.
DR   AlphaFoldDB; O84898; -.
DR   SMR; O84898; -.
DR   STRING; 289397.MBOVPG45_0314; -.
DR   EnsemblBacteria; ADR25362; ADR25362; MBOVPG45_0314.
DR   KEGG; mbv:MBOVPG45_0314; -.
DR   eggNOG; COG0322; Bacteria.
DR   HOGENOM; CLU_014841_3_2_14; -.
DR   OMA; HIECFDN; -.
DR   OrthoDB; 1036075at2; -.
DR   Proteomes; UP000008713; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009381; F:excinuclease ABC activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.340; -; 1.
DR   Gene3D; 3.40.1440.10; -; 1.
DR   HAMAP; MF_00203; UvrC; 1.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR001943; UVR_dom.
DR   InterPro; IPR036876; UVR_dom_sf.
DR   InterPro; IPR004791; UvrC.
DR   InterPro; IPR001162; UvrC_RNase_H_dom.
DR   InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF02151; UVR; 1.
DR   Pfam; PF08459; UvrC_HhH_N; 1.
DR   SMART; SM00465; GIYc; 1.
DR   SUPFAM; SSF46600; SSF46600; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
DR   PROSITE; PS50151; UVR; 1.
DR   PROSITE; PS50165; UVRC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA excision; DNA repair; Excision nuclease;
KW   SOS response.
FT   CHAIN           1..571
FT                   /note="UvrABC system protein C"
FT                   /id="PRO_0000138316"
FT   DOMAIN          15..93
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   DOMAIN          184..219
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
SQ   SEQUENCE   571 AA;  66463 MW;  717DA202CA50DCE3 CRC64;
     MDKNEIILML KNVSTSPGVY LWKDAKQNVL YVGKAKNLRK RMLQYFDGAI NSYKTNKLVS
     LIYDFDVYIC KTNKEALLLE KAMIDRYNPE FNILLLDDRK YPYLKVQLLK DSLLINLSRK
     VNAKDSKNTF YYGPFPSGYG AKPILKLLQH ETLYENGLLI KNKDYNFWIN QFNKIKEILS
     FKNNNYINEL TNKMHQAANN MQFELALFLR DGLTYLKKLK ESQIIELSQY KNIDVFAYKT
     DEKLIFATVL FYRYGILINK VNLTIPLGLS VDESLRVFFE QFYEDKILPD NLIVQEELLN
     FDLNLSSEYK FISPKIGTNK KVLDLAILNL NDYYEKEHLV IKNQLDKASN MLDSLNKYLN
     LPKLKNIVVF DNSNINNINP VGVAIVYTNG IKNKSLYRKF NLEALNERSA DVEYIKQSIS
     KFFSSNKNTK DYDLVIADGG IQQVNEAKKT LKTLNINIPV IGLVKNEFHK TKALIDLDMN
     EIHINDLELY NYLVQIQVEV DRFAKSHFRN RQKISSLEGK LRNIKGLGPN MEQNLLNHFK
     SYAKIYDASV EELSKIVPLN IAKSIKNKDY E