ID   UVRC_MYCCT              Reviewed;         584 AA.
AC   Q2SSM4;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203};
DE            Short=Protein UvrC {ECO:0000255|HAMAP-Rule:MF_00203};
DE   AltName: Full=Excinuclease ABC subunit C {ECO:0000255|HAMAP-Rule:MF_00203};
GN   Name=uvrC {ECO:0000255|HAMAP-Rule:MF_00203}; OrderedLocusNames=MCAP_0252;
OS   Mycoplasma capricolum subsp. capricolum (strain California kid / ATCC 27343
OS   / NCTC 10154).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=340047;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=California kid / ATCC 27343 / NCTC 10154;
RA   Glass J.I., Lartigue C., Pfannkoch C., Baden-Tillson H., Smith H.O.,
RA   Venter J.C., Roske K., Wise K.S., Calcutt M.J., Nelson W.C., Nierman W.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrC both incises the 5' and 3' sides of the
CC       lesion. The N-terminal half is responsible for the 3' incision and the
CC       C-terminal half is responsible for the 5' incision. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
CC   -!- SUBUNIT: Interacts with UvrB in an incision complex.
CC       {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SIMILARITY: Belongs to the UvrC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
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DR   EMBL; CP000123; ABC01582.1; -; Genomic_DNA.
DR   RefSeq; WP_011387140.1; NC_007633.1.
DR   AlphaFoldDB; Q2SSM4; -.
DR   SMR; Q2SSM4; -.
DR   EnsemblBacteria; ABC01582; ABC01582; MCAP_0252.
DR   GeneID; 23778794; -.
DR   KEGG; mcp:MCAP_0252; -.
DR   HOGENOM; CLU_014841_3_2_14; -.
DR   OMA; HIECFDN; -.
DR   OrthoDB; 1036075at2; -.
DR   PhylomeDB; Q2SSM4; -.
DR   Proteomes; UP000001928; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009381; F:excinuclease ABC activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.340; -; 1.
DR   Gene3D; 3.40.1440.10; -; 1.
DR   HAMAP; MF_00203; UvrC; 1.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR001943; UVR_dom.
DR   InterPro; IPR036876; UVR_dom_sf.
DR   InterPro; IPR004791; UvrC.
DR   InterPro; IPR001162; UvrC_RNase_H_dom.
DR   InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF02151; UVR; 1.
DR   Pfam; PF08459; UvrC_HhH_N; 1.
DR   SMART; SM00465; GIYc; 1.
DR   SUPFAM; SSF46600; SSF46600; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   TIGRFAMs; TIGR00194; uvrC; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
DR   PROSITE; PS50151; UVR; 1.
DR   PROSITE; PS50165; UVRC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA excision; DNA repair; Excision nuclease;
KW   SOS response.
FT   CHAIN           1..584
FT                   /note="UvrABC system protein C"
FT                   /id="PRO_0000264914"
FT   DOMAIN          12..89
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   DOMAIN          194..229
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
SQ   SEQUENCE   584 AA;  68960 MW;  4D745F9AD18DF764 CRC64;
     MNLKEQVDLL TNKPGCYLFL NKDNEVIYVG KAKNLKKRVS TYFNKAYNIK TTRLIREITH
     LKYFIVDNEK ESLLLEKNLI KKYRPKYNVL LNDDKTYPYI IITNQKDPMY KYVRKYEKKA
     LRNYGPLPIG SNARSILLTL QRLFPLRMCK GDLKKPCLYY HLNQCSGACF KTVDSSYYEY
     QIKQVDKFFK GEINQVKQTL VKQMQKASDN LQFEQAKRIK DQITSLDFIT AKQNVDIVTN
     KNIDVVNYEI NEEKICFVML FYRLGQLTYK DEYIQNYEGQ DLDELLNSYL QQIYQKNLYP
     DVLLIPNEID LLDLDENLLE FSSYSFNNQD DIFIKLAKQN AVDSLNKSIL SNNVNSGDEL
     EILDQLQQIS NINKYPKRIE IFDISNIYNQ FITGACIVYI NAKPVRNEFR KYNIDSQYTS
     DYARMKFMLE KRFLKRIKEK EQLPDLIIVD GGIIQIHAAK EVLNKLNLKI NVIGLSKDNN
     HKTRYLIDIF EQTIDIKNFK KLYNFLTSLQ IRVDEYAKSG FRKKYHNQLN DQILLIKGVG
     KKTNLKLYKH FKTIDNIKNA SFDELNKIIN NKKITNLIIS NFKK