ID   UVRC_OLEA2              Reviewed;         700 AA.
AC   Q313T1;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203};
DE            Short=Protein UvrC {ECO:0000255|HAMAP-Rule:MF_00203};
DE   AltName: Full=Excinuclease ABC subunit C {ECO:0000255|HAMAP-Rule:MF_00203};
GN   Name=uvrC {ECO:0000255|HAMAP-Rule:MF_00203}; OrderedLocusNames=Dde_1014;
OS   Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20)
OS   (Desulfovibrio alaskensis).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfovibrionaceae; Oleidesulfovibrio.
OX   NCBI_TaxID=207559;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1058 / DSM 17464 / G20;
RX   PubMed=21685289; DOI=10.1128/jb.05400-11;
RA   Hauser L.J., Land M.L., Brown S.D., Larimer F., Keller K.L.,
RA   Rapp-Giles B.J., Price M.N., Lin M., Bruce D.C., Detter J.C., Tapia R.,
RA   Han C.S., Goodwin L.A., Cheng J.F., Pitluck S., Copeland A., Lucas S.,
RA   Nolan M., Lapidus A.L., Palumbo A.V., Wall J.D.;
RT   "Complete genome sequence and updated annotation of Desulfovibrio
RT   alaskensis G20.";
RL   J. Bacteriol. 193:4268-4269(2011).
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrC both incises the 5' and 3' sides of the
CC       lesion. The N-terminal half is responsible for the 3' incision and the
CC       C-terminal half is responsible for the 5' incision. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
CC   -!- SUBUNIT: Interacts with UvrB in an incision complex.
CC       {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SIMILARITY: Belongs to the UvrC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
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DR   EMBL; CP000112; ABB37815.1; -; Genomic_DNA.
DR   RefSeq; WP_011367052.1; NC_007519.1.
DR   AlphaFoldDB; Q313T1; -.
DR   SMR; Q313T1; -.
DR   STRING; 207559.Dde_1014; -.
DR   EnsemblBacteria; ABB37815; ABB37815; Dde_1014.
DR   KEGG; dde:Dde_1014; -.
DR   eggNOG; COG0322; Bacteria.
DR   HOGENOM; CLU_014841_3_2_7; -.
DR   OMA; HIECFDN; -.
DR   OrthoDB; 1036075at2; -.
DR   Proteomes; UP000002710; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009381; F:excinuclease ABC activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.340; -; 1.
DR   Gene3D; 3.40.1440.10; -; 1.
DR   HAMAP; MF_00203; UvrC; 1.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR001943; UVR_dom.
DR   InterPro; IPR036876; UVR_dom_sf.
DR   InterPro; IPR004791; UvrC.
DR   InterPro; IPR001162; UvrC_RNase_H_dom.
DR   InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF02151; UVR; 1.
DR   Pfam; PF08459; UvrC_HhH_N; 1.
DR   SMART; SM00465; GIYc; 1.
DR   SMART; SM00278; HhH1; 2.
DR   SUPFAM; SSF46600; SSF46600; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   TIGRFAMs; TIGR00194; uvrC; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
DR   PROSITE; PS50151; UVR; 1.
DR   PROSITE; PS50165; UVRC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA excision; DNA repair; Excision nuclease;
KW   Reference proteome; SOS response.
FT   CHAIN           1..700
FT                   /note="UvrABC system protein C"
FT                   /id="PRO_0000227427"
FT   DOMAIN          11..90
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   DOMAIN          200..235
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
SQ   SEQUENCE   700 AA;  75959 MW;  4BC824446441D791 CRC64;
     MDQIDISCIP TTPGVYLYKD PAGKVVYVGK AKHLRRRVAS YFRDIQRHTP KTRAMLRSAA
     TVETLSTTTE KEALLLEASL IKKHRPRYNI LLRDDKQYVL FQLTRKHHWP RLVLTRKVRK
     DGSAYFGPFT SGQAARQTWK VIHKVFPLRR CSDKAFRNRV RPCLYHFMNQ CPGPCVLDVD
     RDGYMQMVRK VEMLLAGRST ELIDMLRADM QAASDALEFE EAALLRDQLQ AVERTVERQA
     AVLPGVHDMD AVGLAEAGGG LALSVLFIRR SVLLDKRNFF WSGLTLEEGP EVLLSFLTQY
     YGPGSFIPPR ILVPWDIRTE DREGAELAPA AVCTDAGLLP DTPLLPDCPE AAPLPAAPVF
     AVSAGDVMPS GHDADPAGTA DAPVVRGDSA PEQPLPAAVP PLCAEESASG SALRAVAEML
     TELRGGPVRV LPPRNATDNQ LVTMATENAR EDARAEKRPD VAGVIAAKLG MSAPPVRIEA
     VDVSHTGGSN TRVGVVVFEN GTPARDQYRT YAFADDEAGG DDTGVLALWA VRRVHSGPPW
     PDLLLVDGGR GQLAAVMTAL ESAGAGGLFA VASIAKARNE ETGRADRRAG NLADRIFLPG
     RSNPVNFKSG SPELLFLQHV RDTVHDYAIG RHRRARSGAA LSGELQRMQG IGPATARLLW
     EHFSSLQEMV DAGEKGLAAL PGIGKAKAAV IHEGLKRLVG