ID   UVRC_PSECP              Reviewed;         674 AA.
AC   B8H7L9;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203};
DE            Short=Protein UvrC {ECO:0000255|HAMAP-Rule:MF_00203};
DE   AltName: Full=Excinuclease ABC subunit C {ECO:0000255|HAMAP-Rule:MF_00203};
GN   Name=uvrC {ECO:0000255|HAMAP-Rule:MF_00203}; OrderedLocusNames=Achl_1823;
OS   Pseudarthrobacter chlorophenolicus (strain ATCC 700700 / DSM 12829 / CIP
OS   107037 / JCM 12360 / KCTC 9906 / NCIMB 13794 / A6) (Arthrobacter
OS   chlorophenolicus).
OC   Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Pseudarthrobacter.
OX   NCBI_TaxID=452863;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700700 / DSM 12829 / CIP 107037 / JCM 12360 / KCTC 9906 / NCIMB
RC   13794 / A6;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA   Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P.;
RT   "Complete sequence of chromosome of Arthrobacter chlorophenolicus A6.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrC both incises the 5' and 3' sides of the
CC       lesion. The N-terminal half is responsible for the 3' incision and the
CC       C-terminal half is responsible for the 5' incision. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
CC   -!- SUBUNIT: Interacts with UvrB in an incision complex.
CC       {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SIMILARITY: Belongs to the UvrC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
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DR   EMBL; CP001341; ACL39799.1; -; Genomic_DNA.
DR   RefSeq; WP_015937019.1; NC_011886.1.
DR   AlphaFoldDB; B8H7L9; -.
DR   SMR; B8H7L9; -.
DR   STRING; 452863.Achl_1823; -.
DR   EnsemblBacteria; ACL39799; ACL39799; Achl_1823.
DR   KEGG; ach:Achl_1823; -.
DR   eggNOG; COG0322; Bacteria.
DR   HOGENOM; CLU_014841_1_1_11; -.
DR   OMA; HIECFDN; -.
DR   OrthoDB; 1036075at2; -.
DR   Proteomes; UP000002505; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009381; F:excinuclease ABC activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.340; -; 1.
DR   Gene3D; 3.40.1440.10; -; 1.
DR   HAMAP; MF_00203; UvrC; 1.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR001943; UVR_dom.
DR   InterPro; IPR036876; UVR_dom_sf.
DR   InterPro; IPR004791; UvrC.
DR   InterPro; IPR001162; UvrC_RNase_H_dom.
DR   InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF02151; UVR; 1.
DR   Pfam; PF08459; UvrC_HhH_N; 1.
DR   SMART; SM00465; GIYc; 1.
DR   SMART; SM00278; HhH1; 2.
DR   SUPFAM; SSF46600; SSF46600; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   TIGRFAMs; TIGR00194; uvrC; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
DR   PROSITE; PS50151; UVR; 1.
DR   PROSITE; PS50165; UVRC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA excision; DNA repair; Excision nuclease;
KW   SOS response.
FT   CHAIN           1..674
FT                   /note="UvrABC system protein C"
FT                   /id="PRO_1000200564"
FT   DOMAIN          16..95
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   DOMAIN          207..242
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
SQ   SEQUENCE   674 AA;  73760 MW;  5FC434238B476F3D CRC64;
     MANPASYRPR TGEIPTNPGV YRFRDPHGRV IYVGKAKSLR SRLNSYFANP AGLLPKTYAM
     VHAASSVEWT VVGSELESLQ LEYTWIKEFK PRFNVVFRDD KTYPYLAVTL GEKYPRVQVM
     RGDKRKGTRY FGPYTAGAIR ETMDTLLRVF PVRSCSAGVF KRAESSGRPC LLGYIDKCSA
     PCVGRISPED HRALAEDFCA FMGGEAKRFT NKLEKQMAAA VARLDYEQAA RIRDDITALR
     KVFERNAVVL AEDTDADVFA LHEDELEAAV QVFHVRGGRI RGQRGWVVEK VEDFTTPDLV
     EHLLQQVYGE DGETHGRLPR EVLVPVAPSN AEELTEWLSG IRGARVDVRV PQRGDKAALM
     STVRENAEHA LKLHKTRRAG DLTVRSQALQ ELQEALDLPV PLLRIECFDV SHVQGTNVVA
     SMVVVEDGLP KKSDYRKFSI TGPAASDDTA AMHDVLTRRF RHYLQDKSAQ VDEDVLEAGT
     AEAAAEAAAD AAAEAAVADT TTPIPKTKFA YPPNLVVVDG GQPQVNAAAR ALADLGIDDV
     YVVGLAKRLE EVWLPDSDFP VILPRTSQGL YLLQRIRDEA HRFAISFHRQ KRGKAMTVSA
     LDGVPGLGAS KRKALLAHFG SVKGVKAATP EELAQAKGIG PALAAAIVSH FTGGGPAAVT
     VPAINMTTGE IIET