ID   UVRC_PSET1              Reviewed;         607 AA.
AC   Q3IIM0;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 2.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203};
DE            Short=Protein UvrC {ECO:0000255|HAMAP-Rule:MF_00203};
DE   AltName: Full=Excinuclease ABC subunit C {ECO:0000255|HAMAP-Rule:MF_00203};
GN   Name=uvrC {ECO:0000255|HAMAP-Rule:MF_00203}; OrderedLocusNames=PSHAa1915;
OS   Pseudoalteromonas translucida (strain TAC 125).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Pseudoalteromonadaceae; Pseudoalteromonas.
OX   NCBI_TaxID=326442;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TAC 125;
RX   PubMed=16169927; DOI=10.1101/gr.4126905;
RA   Medigue C., Krin E., Pascal G., Barbe V., Bernsel A., Bertin P.N.,
RA   Cheung F., Cruveiller S., D'Amico S., Duilio A., Fang G., Feller G., Ho C.,
RA   Mangenot S., Marino G., Nilsson J., Parrilli E., Rocha E.P.C., Rouy Z.,
RA   Sekowska A., Tutino M.L., Vallenet D., von Heijne G., Danchin A.;
RT   "Coping with cold: the genome of the versatile marine Antarctica bacterium
RT   Pseudoalteromonas haloplanktis TAC125.";
RL   Genome Res. 15:1325-1335(2005).
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrC both incises the 5' and 3' sides of the
CC       lesion. The N-terminal half is responsible for the 3' incision and the
CC       C-terminal half is responsible for the 5' incision. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
CC   -!- SUBUNIT: Interacts with UvrB in an incision complex.
CC       {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SIMILARITY: Belongs to the UvrC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAI86979.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CR954246; CAI86979.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_011328581.1; NC_007481.1.
DR   AlphaFoldDB; Q3IIM0; -.
DR   SMR; Q3IIM0; -.
DR   STRING; 326442.PSHAa1915; -.
DR   EnsemblBacteria; CAI86979; CAI86979; PSHAa1915.
DR   KEGG; pha:PSHAa1915; -.
DR   PATRIC; fig|326442.8.peg.1854; -.
DR   eggNOG; COG0322; Bacteria.
DR   HOGENOM; CLU_014841_3_2_6; -.
DR   OrthoDB; 1036075at2; -.
DR   BioCyc; PHAL326442:PSHA_RS09460-MON; -.
DR   Proteomes; UP000006843; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009381; F:excinuclease ABC activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.340; -; 1.
DR   Gene3D; 3.40.1440.10; -; 1.
DR   HAMAP; MF_00203; UvrC; 1.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR001943; UVR_dom.
DR   InterPro; IPR036876; UVR_dom_sf.
DR   InterPro; IPR004791; UvrC.
DR   InterPro; IPR001162; UvrC_RNase_H_dom.
DR   InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF02151; UVR; 1.
DR   Pfam; PF08459; UvrC_HhH_N; 1.
DR   SMART; SM00465; GIYc; 1.
DR   SMART; SM00278; HhH1; 2.
DR   SUPFAM; SSF46600; SSF46600; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   TIGRFAMs; TIGR00194; uvrC; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
DR   PROSITE; PS50151; UVR; 1.
DR   PROSITE; PS50165; UVRC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA excision; DNA repair; Excision nuclease;
KW   Reference proteome; SOS response.
FT   CHAIN           1..607
FT                   /note="UvrABC system protein C"
FT                   /id="PRO_0000264927"
FT   DOMAIN          15..93
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   DOMAIN          202..237
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
SQ   SEQUENCE   607 AA;  68740 MW;  8F9BC688477EF036 CRC64;
     MSEFDHVQFL KTLSSEPGVY CMLDSDNQVI YVGKAKHLKK RVSSYFRSNI TDSKTRVLVS
     NICNVEVTLT NTETEALLLE NNLIKKYQPR YNILLRDDKS YPYILLTNHK HPRLAFHRGS
     RKVKGEYFGP FPSAGAVSES LRLMQKIFPI RQCEDVYYRA RSRPCLQYQL KRCSAPCVNK
     VSDEDYTEQV DYVRKFLTGK SHEVIADLIK KMEAASQQLN FELAAKVRDQ IMLLRKMQEQ
     QSISGNFAEM DVVGFAHLNG LNGIHLLMIR DHKVLGSKTY FPKVPKDSSE QEILTSFLGQ
     YYLAPGATGR IAKEIILPFE IQESDVLGQA LTQISERKVT LKVVTRGERA QYLQLANKNA
     LNSITVKQST QDSINKRYAQ LKATLRLDDI TRMECFDISH TMGENTVASC VVFDSQGPNT
     KEYRRYNVTG ITGGDDYAAM EFALNKRYNK LVDEDKIPDV IFIDGGKGQL GRAEQYFATW
     PHAKMPLLVG VAKGTSRKPG LETLLIDGGR KTIPMDSDAP ALHLIQHIRD ESHRFAIAGH
     RNKRQKQRTQ SLLEEINGVG AKRRQTLLKY LGGMQGVKAA NIEQLKKVPG ISPDMADKIF
     NHLHDKG