ID   UVRC_RHOP2              Reviewed;         695 AA.
AC   Q2J0X3;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203};
DE            Short=Protein UvrC {ECO:0000255|HAMAP-Rule:MF_00203};
DE   AltName: Full=Excinuclease ABC subunit C {ECO:0000255|HAMAP-Rule:MF_00203};
GN   Name=uvrC {ECO:0000255|HAMAP-Rule:MF_00203}; OrderedLocusNames=RPB_1177;
OS   Rhodopseudomonas palustris (strain HaA2).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=316058;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HaA2;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Pelletier D.A.,
RA   Kyrpides N., Anderson I., Oda Y., Harwood C.S., Richardson P.;
RT   "Complete sequence of Rhodopseudomonas palustris HaA2.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrC both incises the 5' and 3' sides of the
CC       lesion. The N-terminal half is responsible for the 3' incision and the
CC       C-terminal half is responsible for the 5' incision. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
CC   -!- SUBUNIT: Interacts with UvrB in an incision complex.
CC       {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SIMILARITY: Belongs to the UvrC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
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DR   EMBL; CP000250; ABD05887.1; -; Genomic_DNA.
DR   RefSeq; WP_011440076.1; NC_007778.1.
DR   AlphaFoldDB; Q2J0X3; -.
DR   SMR; Q2J0X3; -.
DR   STRING; 316058.RPB_1177; -.
DR   EnsemblBacteria; ABD05887; ABD05887; RPB_1177.
DR   KEGG; rpb:RPB_1177; -.
DR   eggNOG; COG0322; Bacteria.
DR   HOGENOM; CLU_014841_3_0_5; -.
DR   OMA; HIECFDN; -.
DR   OrthoDB; 1036075at2; -.
DR   Proteomes; UP000008809; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009381; F:excinuclease ABC activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.340; -; 1.
DR   Gene3D; 3.40.1440.10; -; 1.
DR   HAMAP; MF_00203; UvrC; 1.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR001943; UVR_dom.
DR   InterPro; IPR036876; UVR_dom_sf.
DR   InterPro; IPR004791; UvrC.
DR   InterPro; IPR001162; UvrC_RNase_H_dom.
DR   InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF02151; UVR; 1.
DR   Pfam; PF08459; UvrC_HhH_N; 1.
DR   SMART; SM00465; GIYc; 1.
DR   SMART; SM00278; HhH1; 2.
DR   SUPFAM; SSF46600; SSF46600; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   TIGRFAMs; TIGR00194; uvrC; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
DR   PROSITE; PS50151; UVR; 1.
DR   PROSITE; PS50165; UVRC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA excision; DNA repair; Excision nuclease;
KW   SOS response.
FT   CHAIN           1..695
FT                   /note="UvrABC system protein C"
FT                   /id="PRO_0000264939"
FT   DOMAIN          88..166
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   DOMAIN          276..311
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   REGION          1..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   695 AA;  76774 MW;  69042FC2FAFC1D9C CRC64;
     MNHDPAETRD TAAAPLADTE SPSPVSPELT PHPAPAAQDI DTATAELTVD EDDEARLPEI
     EDDSAEVADG PLAVGRAAIE QAVRLAPTSP GVYRMLNAAH DVLYVGKAKN VKKRLSSYAR
     PTGHVMRIAR MIAATVTVEI ISTSTETEAL LLEANLIKQL RPRFNVLLRD DKSFPYILIT
     GDHWAPQILK HRGAQSRPGR YFGPFASVGA VNRTITALQR AFLVRSCTDS FFESRTRPCL
     LYQIRRCSGP CTGEVDFPGY TELVREAKDF LSGRSRAVKQ ELAVEMEKAS NELEFETAAL
     YRDRLAALSA IQSQQGINPR TVEEADVFAI YQEGGYSCVE VFFFRTGQNW GNRAYFPRAE
     KSFTPEEVLA SFLAQFYDDK PPPKLILLSH DIEDCALLAD ALCIKADRKV EISTPKRGEK
     KELVAHALTN AREALGRKLA DTATQTRLLQ GLATTLGLPK PPQRIEVYDN SHIQGTNAVG
     AMIVAGPDGF IKNQYRKFNI RSEGLTPGDD YAMMREVLER RFKRLAAAKA EGEAAKPNDD
     ETPQWPDLVI IDGGRGQLNA ARGVLTELGL DAEVTLLGVA KGPDRDAGRE TLFMPEREAI
     KLEPRDPVLY FIQRLRDEAH RFVIGSHRKL RKKDIREAGL QEIPGIGPSR KRALLHHFGT
     LKEIERASLG DLGKVPGISA ESARRIFDFF HPGPG