ID   UVRC_RHOPA              Reviewed;         704 AA.
AC   Q6NAL3;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203};
DE            Short=Protein UvrC {ECO:0000255|HAMAP-Rule:MF_00203};
DE   AltName: Full=Excinuclease ABC subunit C {ECO:0000255|HAMAP-Rule:MF_00203};
GN   Name=uvrC {ECO:0000255|HAMAP-Rule:MF_00203}; OrderedLocusNames=RPA1171;
OS   Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=258594;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-98 / CGA009;
RX   PubMed=14704707; DOI=10.1038/nbt923;
RA   Larimer F.W., Chain P., Hauser L., Lamerdin J.E., Malfatti S., Do L.,
RA   Land M.L., Pelletier D.A., Beatty J.T., Lang A.S., Tabita F.R.,
RA   Gibson J.L., Hanson T.E., Bobst C., Torres y Torres J.L., Peres C.,
RA   Harrison F.H., Gibson J., Harwood C.S.;
RT   "Complete genome sequence of the metabolically versatile photosynthetic
RT   bacterium Rhodopseudomonas palustris.";
RL   Nat. Biotechnol. 22:55-61(2004).
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrC both incises the 5' and 3' sides of the
CC       lesion. The N-terminal half is responsible for the 3' incision and the
CC       C-terminal half is responsible for the 5' incision. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
CC   -!- SUBUNIT: Interacts with UvrB in an incision complex.
CC       {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SIMILARITY: Belongs to the UvrC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
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DR   EMBL; BX572596; CAE26614.1; -; Genomic_DNA.
DR   RefSeq; WP_011156735.1; NC_005296.1.
DR   AlphaFoldDB; Q6NAL3; -.
DR   SMR; Q6NAL3; -.
DR   STRING; 258594.RPA1171; -.
DR   PRIDE; Q6NAL3; -.
DR   EnsemblBacteria; CAE26614; CAE26614; RPA1171.
DR   GeneID; 66892192; -.
DR   KEGG; rpa:RPA1171; -.
DR   eggNOG; COG0322; Bacteria.
DR   HOGENOM; CLU_014841_3_0_5; -.
DR   OMA; HIECFDN; -.
DR   PhylomeDB; Q6NAL3; -.
DR   BioCyc; RPAL258594:TX73_RS05975-MON; -.
DR   Proteomes; UP000001426; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009381; F:excinuclease ABC activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.340; -; 1.
DR   Gene3D; 3.40.1440.10; -; 1.
DR   HAMAP; MF_00203; UvrC; 1.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR001943; UVR_dom.
DR   InterPro; IPR036876; UVR_dom_sf.
DR   InterPro; IPR004791; UvrC.
DR   InterPro; IPR001162; UvrC_RNase_H_dom.
DR   InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF02151; UVR; 1.
DR   Pfam; PF08459; UvrC_HhH_N; 1.
DR   SMART; SM00465; GIYc; 1.
DR   SMART; SM00278; HhH1; 2.
DR   SUPFAM; SSF46600; SSF46600; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   TIGRFAMs; TIGR00194; uvrC; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
DR   PROSITE; PS50151; UVR; 1.
DR   PROSITE; PS50165; UVRC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA excision; DNA repair; Excision nuclease;
KW   Reference proteome; SOS response.
FT   CHAIN           1..704
FT                   /note="UvrABC system protein C"
FT                   /id="PRO_0000264936"
FT   DOMAIN          92..170
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   DOMAIN          280..315
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   REGION          1..77
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   704 AA;  77232 MW;  A380EDA55B9C23B0 CRC64;
     MIHDPAEPPA AAAEPPLDTA SPDGAAPVAD TRPAAGNQDI DAATASLAVE EDDEARLPEV
     EDEPEAEPAQ AGAGPMAVGR SAIARAVRLA PTSPGVYRML NAERDVLYVG KAKNVKKRLA
     SYARPTGQVL RIARMIALTV EVEVISTTTE TEALLLEANL IKQLRPRFNV QLRDDKSFPY
     ILITSDHWAP QILKHRGAQS RPGRYFGPFA SAGAVNRTIT ALQRAFLVRS CTDSFFESRT
     RPCLLYQIRR CAGPCTGEVD FPGYSELVRE ATDFLSGRSR AVKELLAAEM EKASGELEFE
     TAALYRDRLA ALSAIQSQQG INPRTVEEAD VFAIHQDGGY SCVEVFFFRT GQNWGNRAYF
     PRAEKSFTPA EVLGAFVAQF YDDKPPPKLI LLSHEIEEAE LLADALCVKA GHKVEITVPK
     RGEKKELVAH AQTNAREALG RKLADTATQA RLLENLATTL GLPKTPQRIE VYDNSHIQGT
     NAVGAMIVAG PDGFIKNQYR KFNIRSEGLT PGDDYAMMRE VLQRRFKRLV TSQAEGDGEA
     AAKAKPKDDD VPQWPDLVII DGGRGQLNAA REALSGIGLT DQVTLLGVAK GPDRDAGRET
     LFLPDRDAIK LEPRDPVLYF IQRLRDEAHR FVIGSHRTLR KKDIREAGLQ EIPGIGPTRK
     RALLLHFGTL KEIERASIAD LGKVPGISAE SAKRIFEFFH ARPD