ID   UVRC_RHOPB              Reviewed;         699 AA.
AC   Q21AW5;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2006, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203};
DE            Short=Protein UvrC {ECO:0000255|HAMAP-Rule:MF_00203};
DE   AltName: Full=Excinuclease ABC subunit C {ECO:0000255|HAMAP-Rule:MF_00203};
GN   Name=uvrC {ECO:0000255|HAMAP-Rule:MF_00203}; OrderedLocusNames=RPC_0901;
OS   Rhodopseudomonas palustris (strain BisB18).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=316056;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BisB18;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Pelletier D.A., Kyrpides N., Anderson I., Oda Y., Harwood C.S.,
RA   Richardson P.;
RT   "Complete sequence of Rhodopseudomonas palustris BisB18.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrC both incises the 5' and 3' sides of the
CC       lesion. The N-terminal half is responsible for the 3' incision and the
CC       C-terminal half is responsible for the 5' incision. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
CC   -!- SUBUNIT: Interacts with UvrB in an incision complex.
CC       {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SIMILARITY: Belongs to the UvrC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
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DR   EMBL; CP000301; ABD86471.1; -; Genomic_DNA.
DR   RefSeq; WP_011471379.1; NC_007925.1.
DR   AlphaFoldDB; Q21AW5; -.
DR   SMR; Q21AW5; -.
DR   STRING; 316056.RPC_0901; -.
DR   PRIDE; Q21AW5; -.
DR   EnsemblBacteria; ABD86471; ABD86471; RPC_0901.
DR   KEGG; rpc:RPC_0901; -.
DR   eggNOG; COG0322; Bacteria.
DR   HOGENOM; CLU_014841_3_0_5; -.
DR   OMA; HIECFDN; -.
DR   OrthoDB; 1036075at2; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009381; F:excinuclease ABC activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.340; -; 1.
DR   Gene3D; 3.40.1440.10; -; 1.
DR   HAMAP; MF_00203; UvrC; 1.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR001943; UVR_dom.
DR   InterPro; IPR036876; UVR_dom_sf.
DR   InterPro; IPR004791; UvrC.
DR   InterPro; IPR001162; UvrC_RNase_H_dom.
DR   InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF02151; UVR; 1.
DR   Pfam; PF08459; UvrC_HhH_N; 1.
DR   SMART; SM00465; GIYc; 1.
DR   SMART; SM00278; HhH1; 2.
DR   SUPFAM; SSF46600; SSF46600; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   TIGRFAMs; TIGR00194; uvrC; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
DR   PROSITE; PS50151; UVR; 1.
DR   PROSITE; PS50165; UVRC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA excision; DNA repair; Excision nuclease;
KW   SOS response.
FT   CHAIN           1..699
FT                   /note="UvrABC system protein C"
FT                   /id="PRO_0000264937"
FT   DOMAIN          92..170
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   DOMAIN          280..315
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   REGION          1..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   699 AA;  76896 MW;  213ED81303381B55 CRC64;
     MIQHPTDTPE VAADAAAEPE RAAGAAGATP QPSQDAVEPA ADVDAATASL AAEDDDEPVL
     PQVPEEAGDE VAAGPLAIGR SAIAQAVRLA PTSPGVYRML NAASDVLYVG KAKNVKKRLA
     SYARPTGHVV RISRMIAATV SVEIISTATE TEALLLEANL IKQLRPRFNV LLRDDKSFPY
     ILITGDHWAP QIIKHRGAQS RPGRYFGPFA SVGSVNRTIT ALQRAFLMRS CTDAFFESRT
     RPCLLYQIKR CAGPCTGEID FPGYTALVRE ATDFLSGRSR LVKQELAGEM EKASAELEFE
     TAALYRDRLA ALSAIQSQQG INPRTVEEAD VFAIHQEGGY FCVEVFFFRT GQNWGNRAYF
     PRAEKTFTVE EVLAAFLAQF YDDKAPPKQI LLSHRIEECE LLAEALCIKS GHKVEILTPQ
     RGEKKELVGH ALTNAREALG RKLADTATQT RLLQGLVTTL KLPHTPKRIE VYDNSHIQGT
     NAVGAMIVAG PDGFIKNQYR KFNIRSEGIT PGDDYGMMRE VLERRFKRLL APPPEAEAGK
     PKPDDEVPQW PDLVIIDGGR GQLNAVQEIF QALGLSTVTL MAVAKGPDRD AGRETLFMPD
     RLPIKLEPRD PVLYFIQRLR DEAHRFVIGS HRKLRKKDIR EAGLQEIPGI GPSRKRALLH
     HFGTLKEIER ASLGDLGKVP GISAESAKRI FDYFHPQPG