ID   UVRC_RHOPS              Reviewed;         695 AA.
AC   Q13BM0;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=UvrABC system protein C {ECO:0000255|HAMAP-Rule:MF_00203};
DE            Short=Protein UvrC {ECO:0000255|HAMAP-Rule:MF_00203};
DE   AltName: Full=Excinuclease ABC subunit C {ECO:0000255|HAMAP-Rule:MF_00203};
GN   Name=uvrC {ECO:0000255|HAMAP-Rule:MF_00203}; OrderedLocusNames=RPD_1281;
OS   Rhodopseudomonas palustris (strain BisB5).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=316057;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BisB5;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Pelletier D.A., Kyrpides N., Lykidis A., Oda Y., Harwood C.S.,
RA   Richardson P.;
RT   "Complete sequence of Rhodopseudomonas palustris BisB5.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: The UvrABC repair system catalyzes the recognition and
CC       processing of DNA lesions. UvrC both incises the 5' and 3' sides of the
CC       lesion. The N-terminal half is responsible for the 3' incision and the
CC       C-terminal half is responsible for the 5' incision. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
CC   -!- SUBUNIT: Interacts with UvrB in an incision complex.
CC       {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00203}.
CC   -!- SIMILARITY: Belongs to the UvrC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00203}.
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DR   EMBL; CP000283; ABE38519.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q13BM0; -.
DR   SMR; Q13BM0; -.
DR   STRING; 316057.RPD_1281; -.
DR   EnsemblBacteria; ABE38519; ABE38519; RPD_1281.
DR   KEGG; rpd:RPD_1281; -.
DR   eggNOG; COG0322; Bacteria.
DR   HOGENOM; CLU_014841_3_0_5; -.
DR   OMA; HIECFDN; -.
DR   OrthoDB; 1036075at2; -.
DR   BioCyc; RPAL316057:RPD_RS06490-MON; -.
DR   Proteomes; UP000001818; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009381; F:excinuclease ABC activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009432; P:SOS response; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.420.340; -; 1.
DR   Gene3D; 3.40.1440.10; -; 1.
DR   HAMAP; MF_00203; UvrC; 1.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR   InterPro; IPR010994; RuvA_2-like.
DR   InterPro; IPR001943; UVR_dom.
DR   InterPro; IPR036876; UVR_dom_sf.
DR   InterPro; IPR004791; UvrC.
DR   InterPro; IPR001162; UvrC_RNase_H_dom.
DR   InterPro; IPR038476; UvrC_RNase_H_dom_sf.
DR   Pfam; PF01541; GIY-YIG; 1.
DR   Pfam; PF02151; UVR; 1.
DR   Pfam; PF08459; UvrC_HhH_N; 1.
DR   SMART; SM00465; GIYc; 1.
DR   SMART; SM00278; HhH1; 2.
DR   SUPFAM; SSF46600; SSF46600; 1.
DR   SUPFAM; SSF47781; SSF47781; 1.
DR   SUPFAM; SSF82771; SSF82771; 1.
DR   TIGRFAMs; TIGR00194; uvrC; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
DR   PROSITE; PS50151; UVR; 1.
DR   PROSITE; PS50165; UVRC; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA damage; DNA excision; DNA repair; Excision nuclease;
KW   SOS response.
FT   CHAIN           1..695
FT                   /note="UvrABC system protein C"
FT                   /id="PRO_0000264938"
FT   DOMAIN          88..166
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   DOMAIN          276..311
FT                   /note="UVR"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00203"
FT   REGION          1..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   695 AA;  76470 MW;  3D1F164BA2E97A1A CRC64;
     MNQDPAETRD TAAPPPADTT SPSPVSPELE PRSAPGAQDI DAASASLTVD EDDEARLPEI
     DDDSAEVADG PLAVGRAAIE QAVRLAPTSP GVYRMLNAAD DVLYVGKAKN VKKRLSSYAR
     PTGHVVRIAR MIAATVTVEI ISTATETEAL LLEANLIKQL RPRFNVLLRD DKSFPYILIT
     GDHWAPQILK HRGAQSRPGR YFGPFASVGA VNRTITALQR AFLVRSCTDS FFESRTRPCL
     LYQIRRCAGP CTGEVDFPGY TELVREATDF LSGRSRAVKQ ELAVEMEKAS NELEFETAAL
     YRDRLAALSA IQSQQGINPR TVEEADVFAI HQEGGYSCVE VFFFRTGQNW GNRAYFPRAE
     KSFTPEEVLA SFLAQFYDDK PPPKLILLSH DIEECELLAN ALCIKAGRKV EVAAPKRGEK
     KELVAHALTN AREALGRKLA DTATQTRLMQ GLATTLGLPR PPQRIEVYDN SHIQGTNAVG
     AMIVAGPDGF IKNQYRKFNI RSEGLTPGDD YAMMREVLQR RFKRLAAAKA EGDAAKPKED
     DTPLWPDLVI IDGGRGQLNA ARGVLTELGL GAEVTLLGVA KGPDRDAGRE TLFMPEREAI
     KLEPRDPVLY FIQRLRDEAH RFVIGSHRKL RKKDIREAGL QEIPGIGPTR KRALLHHFGT
     LKEIERASIG DLGKVPGISA ESARRIFDFF HPGPG