ID   UVSE_BACAA              Reviewed;         317 AA.
AC   C3P2A9;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=UV DNA damage endonuclease {ECO:0000255|HAMAP-Rule:MF_00606};
DE            Short=UV-endonuclease {ECO:0000255|HAMAP-Rule:MF_00606};
DE            Short=UVED {ECO:0000255|HAMAP-Rule:MF_00606};
DE            EC=3.-.-.- {ECO:0000255|HAMAP-Rule:MF_00606};
GN   Name=uvsE {ECO:0000255|HAMAP-Rule:MF_00606}; OrderedLocusNames=BAA_5617;
OS   Bacillus anthracis (strain A0248).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=592021;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=A0248;
RA   Dodson R.J., Munk A.C., Bruce D., Detter C., Tapia R., Sutton G., Sims D.,
RA   Brettin T.;
RT   "Genome sequence of Bacillus anthracis A0248.";
RL   Submitted (APR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component in a DNA repair pathway. Removal of UV LIGHT
CC       damaged nucleotides. Recognizes pyrimidine dimers and cleave a
CC       phosphodiester bond immediately 5' to the lesion (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the uve1/UvsE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00606}.
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DR   EMBL; CP001598; ACQ47413.1; -; Genomic_DNA.
DR   RefSeq; WP_000605872.1; NC_012659.1.
DR   AlphaFoldDB; C3P2A9; -.
DR   SMR; C3P2A9; -.
DR   GeneID; 45025177; -.
DR   KEGG; bai:BAA_5617; -.
DR   HOGENOM; CLU_017168_0_1_9; -.
DR   OMA; VFDAHHH; -.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   GO; GO:0006290; P:pyrimidine dimer repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009411; P:response to UV; IEA:InterPro.
DR   HAMAP; MF_00606; UV_endonuclease; 1.
DR   InterPro; IPR004601; UvdE.
DR   InterPro; IPR023520; UvdE_bac.
DR   InterPro; IPR036237; Xyl_isomerase-like_sf.
DR   PANTHER; PTHR31290; PTHR31290; 1.
DR   Pfam; PF03851; UvdE; 1.
DR   SUPFAM; SSF51658; SSF51658; 1.
DR   TIGRFAMs; TIGR00629; uvde; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA excision; DNA repair; Endonuclease; Hydrolase; Nuclease.
FT   CHAIN           1..317
FT                   /note="UV DNA damage endonuclease"
FT                   /id="PRO_1000197851"
SQ   SEQUENCE   317 AA;  36818 MW;  1871FC903CEC485A CRC64;
     MIMRFGYVSH AMALWDCSPA KTITFTSFQK LSKQEREDKL YDVTKQNLEH TIRILHYNIA
     HEIPLYRLSS SIVPLATHPE VEFDYIGAFT PLWRKIGALI KEHNLRISFH PNQFTLFTSD
     KPHITTNAIT DMTYHYKVLD AIGIADSSYI NIHVGGAYGN KEKAIERFHE NIKKLPAHIK
     KQMTLENDDK TCTTAETLSI CQKEKIPFVF DYHHHMANLC EEPLEELLPA IFETWSHTNI
     VPKVHISSPK SKKEFRAHAE YIDLEFIKPF LHVAKKINHN FDIMIESKQK DLAMLQFIQE
     LSSIRGIKRI SSSTLQW