ID   UVSE_BACC2              Reviewed;         317 AA.
AC   B7IR00;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=UV DNA damage endonuclease {ECO:0000255|HAMAP-Rule:MF_00606};
DE            Short=UV-endonuclease {ECO:0000255|HAMAP-Rule:MF_00606};
DE            Short=UVED {ECO:0000255|HAMAP-Rule:MF_00606};
DE            EC=3.-.-.- {ECO:0000255|HAMAP-Rule:MF_00606};
GN   Name=uvsE {ECO:0000255|HAMAP-Rule:MF_00606};
GN   OrderedLocusNames=BCG9842_B5482;
OS   Bacillus cereus (strain G9842).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=405531;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G9842;
RA   Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A.,
RA   Ravel J., Sutton G.;
RT   "Genome sequence of Bacillus cereus G9842.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component in a DNA repair pathway. Removal of UV LIGHT
CC       damaged nucleotides. Recognizes pyrimidine dimers and cleave a
CC       phosphodiester bond immediately 5' to the lesion (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the uve1/UvsE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00606}.
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DR   EMBL; CP001186; ACK93488.1; -; Genomic_DNA.
DR   RefSeq; WP_014895365.1; NC_011772.1.
DR   AlphaFoldDB; B7IR00; -.
DR   SMR; B7IR00; -.
DR   EnsemblBacteria; ACK93488; ACK93488; BCG9842_B5482.
DR   KEGG; bcg:BCG9842_B5482; -.
DR   HOGENOM; CLU_017168_0_1_9; -.
DR   OMA; VFDAHHH; -.
DR   Proteomes; UP000006744; Chromosome.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   GO; GO:0006290; P:pyrimidine dimer repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009411; P:response to UV; IEA:InterPro.
DR   HAMAP; MF_00606; UV_endonuclease; 1.
DR   InterPro; IPR004601; UvdE.
DR   InterPro; IPR023520; UvdE_bac.
DR   InterPro; IPR036237; Xyl_isomerase-like_sf.
DR   PANTHER; PTHR31290; PTHR31290; 1.
DR   Pfam; PF03851; UvdE; 1.
DR   SUPFAM; SSF51658; SSF51658; 1.
DR   TIGRFAMs; TIGR00629; uvde; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA excision; DNA repair; Endonuclease; Hydrolase; Nuclease.
FT   CHAIN           1..317
FT                   /note="UV DNA damage endonuclease"
FT                   /id="PRO_1000130230"
SQ   SEQUENCE   317 AA;  36985 MW;  486572C989719B50 CRC64;
     MIMRFGYVSH AMALWDCSPA KTMTFTSFKK LSKQEREDKL YHVIRQNLEH TIRILHYNIA
     HEIPLYRLSS SIVPLATHPE VEFDYIGVFT PLWRKIGALI KEHNLRISFH PNQFTLFTSD
     KPHITTNAIT DMTYHYKILD AIGIADSSYI NIHVGGAYGN KEKAIERFHE NIKKLPAHIK
     KQMTLENDDK TYTTSETLSI CQKENIPFVF DYHHHMANLC EQPLEELLPA IFETWSHTNI
     SPKVHISSPR SEKEFRAHAE YIDLEFIKPF LHVAKKNNHN FDIMIESKQK DLALFRLIDE
     LSAIRGIKRI SGAMLQW