ID   UVSE_BACC4              Reviewed;         317 AA.
AC   B7HFP5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=UV DNA damage endonuclease {ECO:0000255|HAMAP-Rule:MF_00606};
DE            Short=UV-endonuclease {ECO:0000255|HAMAP-Rule:MF_00606};
DE            Short=UVED {ECO:0000255|HAMAP-Rule:MF_00606};
DE            EC=3.-.-.- {ECO:0000255|HAMAP-Rule:MF_00606};
GN   Name=uvsE {ECO:0000255|HAMAP-Rule:MF_00606};
GN   OrderedLocusNames=BCB4264_A5470;
OS   Bacillus cereus (strain B4264).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=405532;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B4264;
RA   Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A.,
RA   Ravel J., Sutton G.;
RT   "Genome sequence of Bacillus cereus B4264.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component in a DNA repair pathway. Removal of UV LIGHT
CC       damaged nucleotides. Recognizes pyrimidine dimers and cleave a
CC       phosphodiester bond immediately 5' to the lesion (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the uve1/UvsE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00606}.
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DR   EMBL; CP001176; ACK63575.1; -; Genomic_DNA.
DR   RefSeq; WP_011110499.1; NZ_VEHB01000004.1.
DR   AlphaFoldDB; B7HFP5; -.
DR   SMR; B7HFP5; -.
DR   EnsemblBacteria; ACK63575; ACK63575; BCB4264_A5470.
DR   KEGG; bcb:BCB4264_A5470; -.
DR   HOGENOM; CLU_017168_0_1_9; -.
DR   OMA; VFDAHHH; -.
DR   Proteomes; UP000007096; Chromosome.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   GO; GO:0006290; P:pyrimidine dimer repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009411; P:response to UV; IEA:InterPro.
DR   HAMAP; MF_00606; UV_endonuclease; 1.
DR   InterPro; IPR004601; UvdE.
DR   InterPro; IPR023520; UvdE_bac.
DR   InterPro; IPR036237; Xyl_isomerase-like_sf.
DR   PANTHER; PTHR31290; PTHR31290; 1.
DR   Pfam; PF03851; UvdE; 1.
DR   SUPFAM; SSF51658; SSF51658; 1.
DR   TIGRFAMs; TIGR00629; uvde; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA excision; DNA repair; Endonuclease; Hydrolase; Nuclease.
FT   CHAIN           1..317
FT                   /note="UV DNA damage endonuclease"
FT                   /id="PRO_1000130231"
SQ   SEQUENCE   317 AA;  36991 MW;  A6AC35F5800A22C3 CRC64;
     MLIRFGYVSH AMALWDCSPA KTMTFTSFKK LSKQEREDKL YHVIRQNLEH TIRILHYNIA
     HEIPLYRLSS SIVPLATHPE VEFDYIGVFT PLWRKIGALI KEHNLRISFH PNQFTLFTSD
     KPHITTNAIT DMTYHYKILD AIGIADSSYI NIHVGGAYGN KEKAIERFHE NIKKLPTHIK
     KQMTLENDDK TYTTAETLSI CQKENIPFVF DYHHHMANLC EEPLEELLPA IFETWSHTNI
     SPKVHISSPR SEKEFRAHAE YIDLEFIKPF LHIAKKHNHN FDIMIESKQK DLALFQLIDE
     LSAIRGIKRI SGAMLQW