ID   UVSE_BACCQ              Reviewed;         317 AA.
AC   B9IRY0;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 62.
DE   RecName: Full=UV DNA damage endonuclease {ECO:0000255|HAMAP-Rule:MF_00606};
DE            Short=UV-endonuclease {ECO:0000255|HAMAP-Rule:MF_00606};
DE            Short=UVED {ECO:0000255|HAMAP-Rule:MF_00606};
DE            EC=3.-.-.- {ECO:0000255|HAMAP-Rule:MF_00606};
GN   Name=uvsE {ECO:0000255|HAMAP-Rule:MF_00606}; OrderedLocusNames=BCQ_5188;
OS   Bacillus cereus (strain Q1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=361100;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Q1;
RX   PubMed=19060151; DOI=10.1128/jb.01629-08;
RA   Xiong Z., Jiang Y., Qi D., Lu H., Yang F., Yang J., Chen L., Sun L., Xu X.,
RA   Xue Y., Zhu Y., Jin Q.;
RT   "Complete genome sequence of the extremophilic Bacillus cereus strain Q1
RT   with industrial applications.";
RL   J. Bacteriol. 191:1120-1121(2009).
CC   -!- FUNCTION: Component in a DNA repair pathway. Removal of UV LIGHT
CC       damaged nucleotides. Recognizes pyrimidine dimers and cleave a
CC       phosphodiester bond immediately 5' to the lesion (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the uve1/UvsE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00606}.
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DR   EMBL; CP000227; ACM15588.1; -; Genomic_DNA.
DR   RefSeq; WP_000605891.1; NC_011969.1.
DR   AlphaFoldDB; B9IRY0; -.
DR   SMR; B9IRY0; -.
DR   EnsemblBacteria; ACM15588; ACM15588; BCQ_5188.
DR   KEGG; bcq:BCQ_5188; -.
DR   HOGENOM; CLU_017168_0_1_9; -.
DR   OMA; VFDAHHH; -.
DR   Proteomes; UP000000441; Chromosome.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   GO; GO:0006290; P:pyrimidine dimer repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0009411; P:response to UV; IEA:InterPro.
DR   HAMAP; MF_00606; UV_endonuclease; 1.
DR   InterPro; IPR004601; UvdE.
DR   InterPro; IPR023520; UvdE_bac.
DR   InterPro; IPR036237; Xyl_isomerase-like_sf.
DR   PANTHER; PTHR31290; PTHR31290; 1.
DR   Pfam; PF03851; UvdE; 1.
DR   SUPFAM; SSF51658; SSF51658; 1.
DR   TIGRFAMs; TIGR00629; uvde; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA excision; DNA repair; Endonuclease; Hydrolase; Nuclease.
FT   CHAIN           1..317
FT                   /note="UV DNA damage endonuclease"
FT                   /id="PRO_1000197854"
SQ   SEQUENCE   317 AA;  36949 MW;  4FE50DF08278542C CRC64;
     MIMRFGYVSH AMALWDCSPA KTMTFTSFQK LSKQEREDKL YDVTRQNLEH TIRILHYNIA
     HEIPLYRLSS SIVPLATHPE VEFDYIGLFT PLWRTIGALI KEHNLRVSFH PNQFTLFTSD
     KPHITTNAIT DMTYHYKVLD AIGIADSSYI NIHVGGAYGN KEKAVERFHD NIKKLPAHIK
     RRMTLENDDK TYTTAETLSI CQKEKIPFVF DYHHHMANLC EEPLEELLPA IFETWSHTNI
     VPKVHISSPK SKKEFRAHAE YIDLEFIKPF LHVAKKINHN FDIMIESKQK DLAMLQFIHE
     LSSIRGVKRI SSSTLQW