ID   CAGE1_MACFA             Reviewed;         840 AA.
AC   Q95JR0; Q4R6M9; Q95JY2;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Cancer-associated gene 1 protein homolog;
DE            Short=CAGE-1;
GN   Name=CAGE1; ORFNames=QtsA-12423, QtsA-14351, QtsA-17576;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC   TISSUE=Testis;
RX   PubMed=12498619; DOI=10.1186/1471-2164-3-36;
RA   Osada N., Hida M., Kusuda J., Tanuma R., Hirata M., Suto Y., Hirai M.,
RA   Terao K., Sugano S., Hashimoto K.;
RT   "Cynomolgus monkey testicular cDNAs for discovery of novel human genes in
RT   the human genome sequence.";
RL   BMC Genomics 3:36-36(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 273-840 (ISOFORM 2).
RC   TISSUE=Testis;
RA   Hashimoto K., Osada N., Hida M., Kusuda J., Tanuma R., Hirai M., Terao K.,
RA   Sugano S.;
RT   "Isolation of novel full-length cDNA clones from macaque testis cDNA
RT   libraries.";
RL   Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q95JR0-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q95JR0-2; Sequence=VSP_023905;
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB62990.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AB070119; BAB63064.1; -; mRNA.
DR   EMBL; AB169153; BAE01246.1; -; mRNA.
DR   EMBL; AB070045; BAB62990.1; ALT_INIT; mRNA.
DR   AlphaFoldDB; Q95JR0; -.
DR   SMR; Q95JR0; -.
DR   STRING; 9541.XP_005554154.1; -.
DR   eggNOG; KOG3650; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   InterPro; IPR029381; CAGE1.
DR   Pfam; PF15066; CAGE1; 2.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Coiled coil; Reference proteome.
FT   CHAIN           1..840
FT                   /note="Cancer-associated gene 1 protein homolog"
FT                   /id="PRO_0000280751"
FT   REGION          800..840
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          303..559
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        800..819
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         648..669
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|Ref.2, ECO:0000303|Ref.3"
FT                   /id="VSP_023905"
FT   CONFLICT        3
FT                   /note="K -> R (in Ref. 2; BAE01246)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        315
FT                   /note="T -> I (in Ref. 2; BAE01246)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   840 AA;  97587 MW;  A875627BE3D4D716 CRC64;
     MNKDYQIFWP SPSDPVRFEV DTSHEKVESI SESDTMNVSN LSQGIMLSDS PICMETTSTT
     CDLPQNEIKN FERENEYEST LCEDAYGTLD NLLNDNNIEN YSKNVLTQPV DTISISSLRQ
     FDTVCKFHCV EAFDDEMTEK PEFQSQVYNY AKDNNIKQDS FREENPMETS VSASTDQLGN
     EYFRQPPPRS PPLIHCSGET LKFPEKSLAK STAKESALNP SQPPSFVCKT AVPSKEIQNY
     GEIPEMSVSY AKEVTAEGVE RPEIVSTWSS AGISWRSKAS QENCEMPDME QSAESLQPVQ
     EDMALNEILK KLKHTNRKQE ARIQELQCSN LYLEKRVKEL QMKTTKQQVF IDVIDKLKEN
     VEELIEEKYK IILEKNDTKK TLQNLQEILA NTQKHLQESR NDKEMLQLQF KKIKANYVRL
     QERYMTEMQQ KNKSVSQYLE MDKTLSKKEE EVKRLQQLRK EQEKVTASAL DLLKREKETQ
     EQEFLSLQEE FQKRDKANLE ERQKLKSRLE KLLTQVKNLQ FMSENERAKN IKLQQQINEV
     KNENKKLKQH VARSEEQNYV PKSETAQLKE QLEEVMKSDI TKDTKMTHSN LLLDCSPCEE
     ESLNPADIER SSQLASKMHS LLALMVGLLK CQDITNSDAE HFKESEKVSD IMLQRLKSLH
     LKKKNLDKEL LKHKDRITTF RDLIAKEKAF QDHAIKVTDC DSDEAKSIRD VPTFLGAKLD
     KYHSLNEELD FLITKLGCLL ESKESHCNRL IEENDKYQRH LGSLIKKVTS YEEIIECADQ
     RLAISHSQIA HLEKRNKHLE DLIRKPREKA RKPRSKSLEN HPKSMTMMPA VFKENRNDLD