ID   CAH11_PIG               Reviewed;         331 AA.
AC   Q866X6;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Carbonic anhydrase-related protein 11;
DE   AltName: Full=CA-RP XI;
DE            Short=CA-XI;
DE            Short=CARP XI;
DE   Flags: Precursor;
GN   Name=CA11;
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Chen Y., Huang C.-H.;
RT   "Molecular identification of carbonic anhydrases (CA) and CA-related (CAR)
RT   genes.";
RL   Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Does not have a catalytic activity.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
CC       {ECO:0000305}.
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DR   EMBL; AY075024; AAL78172.1; -; mRNA.
DR   RefSeq; NP_001004038.1; NM_001004038.1.
DR   AlphaFoldDB; Q866X6; -.
DR   SMR; Q866X6; -.
DR   STRING; 9823.ENSSSCP00000003409; -.
DR   PaxDb; Q866X6; -.
DR   GeneID; 445526; -.
DR   KEGG; ssc:445526; -.
DR   CTD; 770; -.
DR   eggNOG; KOG0382; Eukaryota.
DR   InParanoid; Q866X6; -.
DR   OrthoDB; 1377476at2759; -.
DR   Proteomes; UP000008227; Unplaced.
DR   Proteomes; UP000314985; Unplaced.
DR   GO; GO:0016323; C:basolateral plasma membrane; IBA:GO_Central.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016836; F:hydro-lyase activity; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006730; P:one-carbon metabolic process; IBA:GO_Central.
DR   CDD; cd03121; alpha_CARP_X_XI_like; 1.
DR   Gene3D; 3.10.200.10; -; 1.
DR   InterPro; IPR041878; Alpha_CARP_X/XI.
DR   InterPro; IPR001148; CA_dom.
DR   InterPro; IPR036398; CA_dom_sf.
DR   InterPro; IPR023561; Carbonic_anhydrase_a-class.
DR   PANTHER; PTHR18952; PTHR18952; 1.
DR   Pfam; PF00194; Carb_anhydrase; 1.
DR   SMART; SM01057; Carb_anhydrase; 1.
DR   SUPFAM; SSF51069; SSF51069; 1.
DR   PROSITE; PS51144; ALPHA_CA_2; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..331
FT                   /note="Carbonic anhydrase-related protein 11"
FT                   /id="PRO_0000262535"
FT   DOMAIN          33..306
FT                   /note="Alpha-carbonic anhydrase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01134"
FT   REGION          303..331
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        118
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        170
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        189
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        263
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   331 AA;  36395 MW;  A1E8497B135D2088 CRC64;
     MGGAARLSAP RALVLWAVLG AAAHIGPAPD PEDWWSYKDN LQGNFVPGPP FWGLVNAAWS
     LCAVGKRQSP VDVELKRVLY DPFLPPLRLS TGGEKLRGTL YNTGRHVSFL PAPRPVVNVS
     GGPLLYSHRL SELLLLFGAH DGAGSEHQIN HQGFSAEVQL IHFNQELYGN LSAASRGPNG
     LAILSLFVNV SQVAGNSNPF LSRLLNRDTI TRISYKNDAY FLQDLSLELL FPESFGFITY
     QGSLSTPPCS ETVTWILIDR ALNITSLQMH SLRLLSQNPP SQIFQSLSGN GRPLQPLAHR
     ALRGNRDPRH PERRCRGPNY RLHVDGAPHG R