ID   V10_SPTNK               Reviewed;         226 AA.
AC   B4YNF0;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   23-FEB-2022, entry version 40.
DE   RecName: Full=Putative integrase V10;
OS   Sputnik virophage.
OC   Viruses; Varidnaviria; Bamfordvirae; Preplasmiviricota; Maveriviricetes;
OC   Priklausovirales; Lavidaviridae; Sputnikvirus.
OX   NCBI_TaxID=543939;
OH   NCBI_TaxID=5757; Acanthamoeba polyphaga (Amoeba).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=18690211; DOI=10.1038/nature07218;
RA   La Scola B., Desnues C., Pagnier I., Robert C., Barrassi L., Fournous G.,
RA   Merchat M., Suzan-Monti M., Forterre P., Koonin E., Raoult D.;
RT   "The virophage as a unique parasite of the giant mimivirus.";
RL   Nature 455:100-104(2008).
CC   -!- FUNCTION: May catalyze site-specific integration of viral genome into
CC       host or helper virus DNA.
CC   -!- SIMILARITY: Belongs to the 'phage' integrase family. {ECO:0000305}.
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DR   EMBL; EU606015; ACF16994.1; -; Genomic_DNA.
DR   RefSeq; YP_002122371.1; NC_011132.1.
DR   SMR; B4YNF0; -.
DR   GeneID; 6760345; -.
DR   KEGG; vg:6760345; -.
DR   Proteomes; UP000001863; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   SUPFAM; SSF56349; SSF56349; 1.
PE   3: Inferred from homology;
KW   DNA integration; Reference proteome; Viral genome integration;
KW   Virus entry into host cell.
FT   CHAIN           1..226
FT                   /note="Putative integrase V10"
FT                   /id="PRO_0000369818"
FT   ACT_SITE        97
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        174
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        177
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        210
FT                   /note="O-(3'-phospho-DNA)-tyrosine intermediate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   226 AA;  26136 MW;  4BE950C52DAC2F67 CRC64;
     MPKYTDDDIF DDGAPQVAKG FDRGIDYLDI AAKLKKGLKK NYKVLQDTES TANAKRFAGS
     RVIYIIIALL QLKNCSRISE AIVATKKFSV SKNLNERVVV KIAKSEKDLI DRKTKDKIHT
     KPRYRDMVFP VDLVDTKIFK YIVKTKYWTK FCEFDSPRKR VLDFLLGHYE CNTHSLRYAG
     INYLLNVEKR DMNVVAKFVG HANVNQLVLY TQTKALDEIF DRKIVV