ID   V1A14_RAT               Reviewed;         339 AA.
AC   Q5J3K9;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Vomeronasal type-1 receptor A14;
GN   Name=V1ra14 {ECO:0000312|RGD:1359628};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1] {ECO:0000312|EMBL:AAR87968.1}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Capello L., Rodriguez I.;
RT   "Rat vomeronasal receptors.";
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Putative pheromone receptor implicated in the regulation of
CC       social as well as reproductive behavior.
CC       {ECO:0000250|UniProtKB:Q8VIC6}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR   EMBL; AY510301; AAR87968.1; -; mRNA.
DR   AlphaFoldDB; Q5J3K9; -.
DR   SMR; Q5J3K9; -.
DR   GlyGen; Q5J3K9; 1 site.
DR   UCSC; RGD:1359628; rat.
DR   RGD; 1359628; V1ra14.
DR   InParanoid; Q5J3K9; -.
DR   PhylomeDB; Q5J3K9; -.
DR   PRO; PR:Q5J3K9; -.
DR   Proteomes; UP000002494; Unplaced.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016503; F:pheromone receptor activity; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; IEA:UniProt.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR004072; Vmron_rcpt_1.
DR   PANTHER; PTHR24062; PTHR24062; 1.
DR   Pfam; PF03402; V1R; 1.
DR   PRINTS; PR01534; VOMERONASL1R.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW   Membrane; Pheromone response; Receptor; Reference proteome; Transducer;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..339
FT                   /note="Vomeronasal type-1 receptor A14"
FT                   /id="PRO_0000239970"
FT   TOPO_DOM        1..42
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        43..63
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        64..75
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        76..96
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        97..119
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..140
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        141..160
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        161..181
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        182..213
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        235..264
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        265..285
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        286..296
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        297..317
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        318..339
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        185
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        111..198
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ   SEQUENCE   339 AA;  38487 MW;  0DC3BF1F3ACAC78C CRC64;
     MMGVQICQGM MSEIPFFSPP PQFSYMMNKN IRLHTDSNIR NTFFTDIGIG ISANSLLLLF
     NIFKLTRGQR SRLTDLPIGL LSLINLLMLL MAAFIATDTF ISWKGWDDII CKFLVYLYRT
     FRGLSLCTSC LLSVLQAIIL SPRSSCLAKF KHKPPHHISC AILSLSVLYM FIGSHLLVSI
     IATPNLTTND FIHVTQSCSI LPMSYLMQCM FSTLLAIRDV FLISLMVLST WYMVALLCRH
     RKQTRHLQGT SLSPKASPEQ RATRSILMLM SLFVLMSVFD SIVCSSRTMY LNDPISYSIQ
     LFMVHIYATV SPFVFIVTEK HIVNFLRSVC EGDECLNIH