V1R92_RAT
ID V1R92_RAT Reviewed; 308 AA.
AC Q5J3N1; Q9WUU3;
DT 13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 15-FEB-2005, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=Vomeronasal type-1 receptor 92;
DE AltName: Full=M24 pheromone receptor;
DE AltName: Full=Vomeronasal type-1 receptor B6;
GN Name=Vom1r92; Synonyms=V1rb6;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1] {ECO:0000312|EMBL:CAB44236.1}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Mimmack M.L.;
RL Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000312|EMBL:CAB44236.1}
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Capello L., Rodriguez I.;
RT "Rat vomeronasal receptors.";
RL Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [MRNA] OF 1-284, AND PUTATIVE FUNCTION.
RX PubMed=9757043; DOI=10.1016/s0169-328x(98)00183-1;
RA Saito H., Mimmack M.L., Keverne E.B., Kishimoto J., Emson P.C.;
RT "Isolation of mouse vomeronasal receptor genes and their co-localization
RT with specific G-protein messenger RNAs.";
RL Brain Res. Mol. Brain Res. 60:215-227(1998).
CC -!- FUNCTION: Putative pheromone receptor implicated in the regulation of
CC social as well as reproductive behavior.
CC {ECO:0000250|UniProtKB:Q8VIC6}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000255|PROSITE-ProRule:PRU00521}.
CC -!- CAUTION: Was originally (Ref.1 and PubMed:9757043) thought to originate
CC from mouse. {ECO:0000305}.
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DR EMBL; Y17567; CAB44236.1; -; Genomic_DNA.
DR EMBL; AY510279; AAR87946.1; -; mRNA.
DR AlphaFoldDB; Q5J3N1; -.
DR SMR; Q5J3N1; -.
DR GlyGen; Q5J3N1; 1 site.
DR iPTMnet; Q5J3N1; -.
DR PhosphoSitePlus; Q5J3N1; -.
DR PaxDb; Q5J3N1; -.
DR PRIDE; Q5J3N1; -.
DR UCSC; RGD:1564573; rat.
DR RGD; 1564573; Vom1r92.
DR VEuPathDB; HostDB:ENSRNOG00000065051; -.
DR eggNOG; ENOG502SNRJ; Eukaryota.
DR HOGENOM; CLU_058641_0_0_1; -.
DR InParanoid; Q5J3N1; -.
DR OMA; ICTEKHM; -.
DR PhylomeDB; Q5J3N1; -.
DR PRO; PR:Q5J3N1; -.
DR Proteomes; UP000002494; Chromosome 4.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016503; F:pheromone receptor activity; IEA:InterPro.
DR GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR GO; GO:0007606; P:sensory perception of chemical stimulus; IEA:UniProt.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR004072; Vmron_rcpt_1.
DR PANTHER; PTHR24062; PTHR24062; 1.
DR Pfam; PF03402; V1R; 1.
DR PRINTS; PR01534; VOMERONASL1R.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW Membrane; Pheromone response; Receptor; Reference proteome; Transducer;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..308
FT /note="Vomeronasal type-1 receptor 92"
FT /id="PRO_0000239978"
FT TOPO_DOM 1..18
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 19..39
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 40..48
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 49..69
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 70..91
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 92..112
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TOPO_DOM 113..132
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..153
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TOPO_DOM 154..188
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 189..209
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TOPO_DOM 210..236
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 237..257
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT TOPO_DOM 258..267
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 268..288
FT /note="Helical; Name=7"
FT /evidence="ECO:0000255"
FT TOPO_DOM 289..308
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 157
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 83..170
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
FT CONFLICT 148
FT /note="L -> F (in Ref. 1; CAB44236)"
FT /evidence="ECO:0000305"
FT CONFLICT 185
FT /note="T -> P (in Ref. 1; CAB44236)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 308 AA; 35098 MW; 85ADCFE1D86C2A07 CRC64;
MNKDNTLHTI MKITMFSEVS VGISANSILF FAHLCMLLGE NRPKPFHLYI VSLSLTQLIL
LITMGLIAVD MFMSWGRWDS TPCQSLIYLH RLLRGFTLCA ACLLNVFWMI TLSPRSSCLS
KFKHNSPHHI SGAFLFLCVL YMSFSSHLLV SIIATPNLTS NIFMYVTQSC SLLPMSYSRT
STFSTTIAIR EAFLISLMAL SSGFMVTLLW RHKKQAQHLH STSLSSKASP ERRATRTILL
LMSFFVVLYI LENVVFYSRM KFKDGSMFYC VQIIVSHSYA TISPFVFICT EKHMTKILRS
VCTRIINI
