ID   V1R98_RAT               Reviewed;         314 AA.
AC   Q5J3E5;
DT   13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Vomeronasal type-1 receptor 98;
DE   AltName: Full=Vomeronasal type-1 receptor A8;
GN   Name=Vom1r98; Synonyms=V1ra8;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1] {ECO:0000312|EMBL:AAR88032.1}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Capello L., Rodriguez I.;
RT   "Rat vomeronasal receptors.";
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Putative pheromone receptor implicated in the regulation of
CC       social as well as reproductive behavior.
CC       {ECO:0000250|UniProtKB:Q8VIC6}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR   EMBL; AY510365; AAR88032.1; -; mRNA.
DR   AlphaFoldDB; Q5J3E5; -.
DR   SMR; Q5J3E5; -.
DR   IntAct; Q5J3E5; 1.
DR   GlyGen; Q5J3E5; 1 site.
DR   PaxDb; Q5J3E5; -.
DR   Ensembl; ENSRNOT00000104609; ENSRNOP00000078295; ENSRNOG00000066943.
DR   RGD; 1549694; Vom1r98.
DR   eggNOG; ENOG502SNRJ; Eukaryota.
DR   GeneTree; ENSGT01030000234553; -.
DR   HOGENOM; CLU_058641_0_0_1; -.
DR   InParanoid; Q5J3E5; -.
DR   OMA; ISMYERI; -.
DR   OrthoDB; 1390012at2759; -.
DR   PhylomeDB; Q5J3E5; -.
DR   PRO; PR:Q5J3E5; -.
DR   Proteomes; UP000002494; Chromosome 4.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016503; F:pheromone receptor activity; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR   GO; GO:0007606; P:sensory perception of chemical stimulus; IEA:UniProt.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR004072; Vmron_rcpt_1.
DR   PANTHER; PTHR24062; PTHR24062; 1.
DR   Pfam; PF03402; V1R; 1.
DR   PRINTS; PR01534; VOMERONASL1R.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW   Membrane; Pheromone response; Receptor; Reference proteome; Transducer;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..314
FT                   /note="Vomeronasal type-1 receptor 98"
FT                   /id="PRO_0000239965"
FT   TOPO_DOM        1..19
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        20..40
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        41..49
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        50..70
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        71..92
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..113
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        114..133
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        155..186
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        187..207
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        208..235
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        236..256
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        257..268
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        269..289
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        290..314
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        158
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        84..171
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ   SEQUENCE   314 AA;  35893 MW;  45D3FA33A908DF0A CRC64;
     MNKDTTMYCS AYIRDVFFCE IGVGISANSC LLLFHIFMFI RGHRPRLTDL PIGLMALIHL
     LMLLLAAYIA KDFFMSSGWD DITCKLFIFL HRFFRSLSVC ATCMLSVFQT IILCPQSSHL
     AKFKPNSPYH LSCFFIFMSI FYTSISSHIL IAAIATQNLT SVNLIYITKS CSFLPMSSSM
     QRTFSTLLAF RNAFLIGLMG LSTCYMATLL CRHKTRSQRL QNSKLSPKAT PEQRAIWTLL
     MFMSFFLVMS TFDSIISYSR TIFQGNPSLY CAQILVAHSY AVVSPMLVLS NENRLTNPLI
     SMYERIVRLD FLCW