ID   V26BL_DANRE             Reviewed;         329 AA.
AC   Q6DH23;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Vacuolar protein sorting-associated protein 26B-like;
DE   AltName: Full=Vesicle protein sorting 26B-like;
GN   Name=vps26bl; ORFNames=zgc:92676;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Larval eye;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable component of the retromer complex, a complex
CC       required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from
CC       endosomes to the trans-Golgi network. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm. Membrane; Peripheral membrane protein.
CC       Note=Does not localize to endosomes. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the VPS26 family. {ECO:0000305}.
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DR   EMBL; BC076160; AAH76160.1; -; mRNA.
DR   RefSeq; NP_001002415.1; NM_001002415.2.
DR   AlphaFoldDB; Q6DH23; -.
DR   SMR; Q6DH23; -.
DR   STRING; 7955.ENSDARP00000072251; -.
DR   PaxDb; Q6DH23; -.
DR   GeneID; 436688; -.
DR   KEGG; dre:436688; -.
DR   CTD; 436688; -.
DR   ZFIN; ZDB-GENE-040718-112; vps26bl.
DR   eggNOG; KOG3063; Eukaryota.
DR   InParanoid; Q6DH23; -.
DR   OrthoDB; 987411at2759; -.
DR   PhylomeDB; Q6DH23; -.
DR   PRO; PR:Q6DH23; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0005768; C:endosome; IBA:GO_Central.
DR   GO; GO:0030904; C:retromer complex; IBA:GO_Central.
DR   GO; GO:0006886; P:intracellular protein transport; IBA:GO_Central.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IBA:GO_Central.
DR   Gene3D; 2.60.40.640; -; 2.
DR   InterPro; IPR014752; Arrestin-like_C.
DR   InterPro; IPR028934; Vps26-related.
DR   PANTHER; PTHR12233; PTHR12233; 1.
DR   Pfam; PF03643; Vps26; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Membrane; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..329
FT                   /note="Vacuolar protein sorting-associated protein 26B-
FT                   like"
FT                   /id="PRO_0000247093"
SQ   SEQUENCE   329 AA;  38377 MW;  2D85E264EC3F3FFE CRC64;
     MSFFSFGQSA EIDIVLNDAE TRKKAEHKTE DGKKDKYFLF YDGETVSGKV NVTLKTPGKR
     LEHQGFKIEF IGQIELYYDR GNHHEFVSLV KDLARPGEMA QSQTFDFEFT HVEKPYESYT
     GQNVKLRYFL RATVSRRLND ICKEMDIVVH TLSTYPELNS SIKMEVGIED CLHIEFEYNK
     SKYHLKDVIV GKIYFLLVRI KIKHMEIDII KRETTGTGPN VYHENDTIAK YEIMDGAPVR
     GESIPIRLFL AGYEMTPTMR DINKKFSVRY YLNLVLIDEE ERRYFKQQEI TLWREGDVAR
     KSMSHQAAIA SQRFEGSEKT LPQAKEDSN