ID   VA203_VACCW             Reviewed;         309 AA.
AC   Q01223; Q01224; Q80HT5;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 2.
DT   23-FEB-2022, entry version 79.
DE   RecName: Full=Ankyrin repeat protein VACWR203;
GN   OrderedLocusNames=VACWR203;
OS   Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain
OS   WR)).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Chordopoxvirinae; Orthopoxvirus; Vaccinia virus.
OX   NCBI_TaxID=10254;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2045793; DOI=10.1099/0022-1317-72-6-1349;
RA   Smith G.L., Chan Y.S., Howard S.T.;
RT   "Nucleotide sequence of 42 kbp of vaccinia virus strain WR from near the
RT   right inverted terminal repeat.";
RL   J. Gen. Virol. 72:1349-1376(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Esposito J.J., Frace A.M., Sammons S.A., Olsen-Rasmussen M., Osborne J.,
RA   Wohlhueter R.;
RT   "Sequencing of the coding region of Vaccinia-WR to an average 9-fold
RT   redundancy and an error rate of 0.16/10kb.";
RL   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- MISCELLANEOUS: Corresponds to the C-terminal part of Kelch repeat and
CC       BTB domain-containing protein 2 in cowpoxvirus.
CC   -!- SIMILARITY: Belongs to the orthopoxviruses VACWR203 protein family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA01849.1; Type=Frameshift; Evidence={ECO:0000305};
CC       Sequence=BAA01850.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; D11079; BAA01849.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; D11079; BAA01850.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AY243312; AAO89482.1; -; Genomic_DNA.
DR   PIR; JQ1813; JQ1813.
DR   PIR; JQ1814; JQ1814.
DR   RefSeq; YP_233085.1; NC_006998.1.
DR   SMR; Q01223; -.
DR   DNASU; 3707580; -.
DR   GeneID; 3707580; -.
DR   KEGG; vg:3707580; -.
DR   Proteomes; UP000000344; Genome.
DR   Gene3D; 1.25.40.20; -; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   Pfam; PF00023; Ank; 2.
DR   Pfam; PF12796; Ank_2; 1.
DR   SMART; SM00248; ANK; 5.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
PE   3: Inferred from homology;
KW   ANK repeat; Reference proteome; Repeat.
FT   CHAIN           1..309
FT                   /note="Ankyrin repeat protein VACWR203"
FT                   /id="PRO_0000067092"
FT   REPEAT          13..44
FT                   /note="ANK 1"
FT   REPEAT          110..142
FT                   /note="ANK 2"
FT   REPEAT          160..189
FT                   /note="ANK 3"
FT   REPEAT          197..231
FT                   /note="ANK 4"
FT   REPEAT          269..298
FT                   /note="ANK 5"
SQ   SEQUENCE   309 AA;  36399 MW;  06BA0FEBAD721B9D CRC64;
     MEMYPRHRYS KHSVFKGFSD KVRKNDLDMN VVKELLSNGA SLTIKDSSNK DPITVYFRRT
     IMNLEMIDER KYIVHSYLKN YKNFDYPFFR KLVLTNKHCL NNYYNISDSK YGTPLHILAS
     NKKLITPNYM KLLVYNGNDI NARGEDTQMR TPLHKYLCKF VYHNIEYGIR YYNEKIIDAF
     IELGADLTIP NDDGMIPVVY CIHSNAEYGY NNITNIKIIR KLLNLSRRAS HNLFRDRVMH
     DYISNTYIDL ECLDIIRSLD GFDINGYFEG RTPLHCAIQH NFTQIAKYLL DRGADIVVPN
     TLIIHQYIQ