ID   VA2_SOLRI               Reviewed;         119 AA.
AC   P35776;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1999, sequence version 2.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Venom allergen 2;
DE   AltName: Full=Allergen Sol r II;
DE   AltName: Full=Venom allergen II;
DE   AltName: Allergen=Sol r 2;
OS   Solenopsis richteri (Black imported fire ant).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Solenopsis.
OX   NCBI_TaxID=30203;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=9389299; DOI=10.1016/s0091-6749(97)70173-8;
RA   Hoffman D.R.;
RT   "Reactions to less common species of fire ants.";
RL   J. Allergy Clin. Immunol. 100:679-683(1997).
RN   [2]
RP   PROTEIN SEQUENCE OF 1-20.
RC   TISSUE=Venom;
RX   PubMed=2355158; DOI=10.1016/0091-6749(90)90042-3;
RA   Hoffman D.R., Smith A.M., Schmidt M., Moffitt J.E., Guralnick M.;
RT   "Allergens in Hymenoptera venom. XXII. Comparison of venoms from two
RT   species of imported fire ants, Solenopsis invicta and richteri.";
RL   J. Allergy Clin. Immunol. 85:988-996(1990).
CC   -!- SUBUNIT: Homodimer; disulfide-linked.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- ALLERGEN: Causes an allergic reaction in human. The most common cause
CC       of insect venom allergy in the southeastern United States is the
CC       imported fire ant.
CC   -!- SIMILARITY: Belongs to the ant venom allergen 2/4 family.
CC       {ECO:0000305}.
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DR   PIR; A58853; A58853.
DR   PIR; E60727; E60727.
DR   AlphaFoldDB; P35776; -.
DR   SMR; P35776; -.
DR   Allergome; 3485; Sol r 2.0101.
DR   Allergome; 635; Sol r 2.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   CDD; cd12800; Sol_i_2; 1.
DR   Gene3D; 1.10.238.190; -; 1.
DR   InterPro; IPR020181; Ant_venom_allergen_Sol_i_2.
DR   InterPro; IPR038211; Ant_venon_allerg_soli_2/4_sf.
PE   1: Evidence at protein level;
KW   Allergen; Direct protein sequencing; Disulfide bond; Secreted.
FT   CHAIN           1..119
FT                   /note="Venom allergen 2"
FT                   /id="PRO_0000065755"
SQ   SEQUENCE   119 AA;  13354 MW;  7347A42798342376 CRC64;
     DIEAQRVLRK DIAECARTLP KCVNQPDDPL ARVDVWHCAM SKRGVYDNPD PAVVKEKNSK
     MCPKIITDPA DVENCKKVVS RCVDRETQRP RSNRQKAINI TGCILRAGVV EATVLAREK