ID   VA2_SOLSV               Reviewed;         138 AA.
AC   A5X2H7;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 27.
DE   RecName: Full=Venom allergen 2;
DE   AltName: Allergen=Sol s 2;
DE   Flags: Precursor;
OS   Solenopsis saevissima (Fire ant) (Myrmecia saevissima).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Solenopsis.
OX   NCBI_TaxID=176597;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Brochetto Braga M.R., Do Nascimento R.C., Alvares L.E., Da Silva G.P.,
RA   Coutinho L.L., Colombo Arnoldi F.G., Viviani V.R.;
RT   "cDNA cloning and characterization of the venom allergens from Solenopsis
RT   saevissima.";
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Homodimer; disulfide-linked. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- ALLERGEN: Causes an allergic reaction in human. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ant venom allergen 2/4 family.
CC       {ECO:0000305}.
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DR   EMBL; DQ342279; ABC58726.1; -; mRNA.
DR   AlphaFoldDB; A5X2H7; -.
DR   SMR; A5X2H7; -.
DR   Allergome; 3488; Sol s 2.0101.
DR   Allergome; 638; Sol s 2.
DR   PRIDE; A5X2H7; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   CDD; cd12800; Sol_i_2; 1.
DR   Gene3D; 1.10.238.190; -; 1.
DR   InterPro; IPR020181; Ant_venom_allergen_Sol_i_2.
DR   InterPro; IPR038211; Ant_venon_allerg_soli_2/4_sf.
PE   2: Evidence at transcript level;
KW   Allergen; Disulfide bond; Secreted; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..138
FT                   /note="Venom allergen 2"
FT                   /id="PRO_0000300483"
SQ   SEQUENCE   138 AA;  15231 MW;  674F274DAE53534A CRC64;
     MKSFVLATCL LGFAQIIYAD TEKLKILRKD IAKCARTLPK CVNQPDDPLA RVDVWHCALA
     KSGVFDDPDP AAIKKKYKKF CAIAVTDPAN VENCKKVTSR CVDKETQCSK SNRQKAINIA
     ACILRSGVTE TTVLAREK