ID   VA3_DINQU               Reviewed;         231 AA.
AC   P0DSI3;
DT   08-MAY-2019, integrated into UniProtKB/Swiss-Prot.
DT   08-MAY-2019, sequence version 1.
DT   25-MAY-2022, entry version 10.
DE   RecName: Full=Venom allergen 3 homolog {ECO:0000250|UniProtKB:P35778};
DE   AltName: Full=Cysteine-rich venom protein {ECO:0000305};
DE            Short=CRVP {ECO:0000305};
DE   Flags: Precursor;
OS   Dinoponera quadriceps (South American ant).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Ponerinae; Ponerini; Dinoponera.
OX   NCBI_TaxID=609295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RX   PubMed=24498135; DOI=10.1371/journal.pone.0087556;
RA   Torres A.F., Huang C., Chong C.M., Leung S.W., Prieto-da-Silva A.R.,
RA   Havt A., Quinet Y.P., Martins A.M., Lee S.M., Radis-Baptista G.;
RT   "Transcriptome analysis in venom gland of the predatory giant ant
RT   Dinoponera quadriceps: insights into the polypeptide toxin arsenal of
RT   hymenopterans.";
RL   PLoS ONE 9:E87556-E87556(2014).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:24498135}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC       {ECO:0000305|PubMed:24498135}.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
CC       {ECO:0000250|UniProtKB:P35778}.
CC   -!- SIMILARITY: Belongs to the CRISP family. {ECO:0000305}.
CC   -!- WEB RESOURCE: Name=National Center for Biotechnology Information
CC       (NCBI);
CC       URL="https://www.ncbi.nlm.nih.gov/nuccore/GANS01000010";
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DR   RefSeq; XP_014469499.1; XM_014614013.1.
DR   AlphaFoldDB; P0DSI3; -.
DR   SMR; P0DSI3; -.
DR   GeneID; 106741736; -.
DR   KEGG; dqu:106741736; -.
DR   Proteomes; UP000515204; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.33.10; -; 1.
DR   InterPro; IPR018244; Allrgn_V5/Tpx1_CS.
DR   InterPro; IPR014044; CAP_domain.
DR   InterPro; IPR035940; CAP_sf.
DR   InterPro; IPR001283; CRISP-related.
DR   InterPro; IPR034763; P14a_insect.
DR   InterPro; IPR002413; V5_allergen-like.
DR   PANTHER; PTHR10334; PTHR10334; 1.
DR   Pfam; PF00188; CAP; 1.
DR   PIRSF; PIRSF038921; P14a; 1.
DR   PRINTS; PR00838; V5ALLERGEN.
DR   PRINTS; PR00837; V5TPXLIKE.
DR   SMART; SM00198; SCP; 1.
DR   SUPFAM; SSF55797; SSF55797; 1.
DR   PROSITE; PS01010; CRISP_2; 1.
PE   2: Evidence at transcript level;
KW   Allergen; Disulfide bond; Glycoprotein; Reference proteome; Secreted;
KW   Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..231
FT                   /note="Venom allergen 3 homolog"
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000447048"
FT   DOMAIN          68..215
FT                   /note="SCP"
FT   CARBOHYD        145
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   DISULFID        25..40
FT                   /evidence="ECO:0000250|UniProtKB:P35778"
FT   DISULFID        30..124
FT                   /evidence="ECO:0000250|UniProtKB:P35778"
FT   DISULFID        51..117
FT                   /evidence="ECO:0000250|UniProtKB:P35778"
FT   DISULFID        196..213
FT                   /evidence="ECO:0000250|UniProtKB:P35778"
SQ   SEQUENCE   231 AA;  25883 MW;  3416168A3C73E6BB CRC64;
     MSSCMLFFTV IIAGVFMGTI ATNYCNLKSC VNYGNIHTMC KYTSSTPAST CSKWEKAGLT
     DAEKKTIVTL HNQLRRKVAA GKETRGNPGP QPAAATMPDL TWDNELAMVA QRWANQCKYG
     HDACRNIERF QVGQNVAIRG STGENLSTVD QMILSWYSEV DLMNKKYVSS FPKDDTYKKI
     GHYTQIVYGN TKTIGCGRIF YKDGKWNQQY LVCNYGPAGN YPNAPVYQIK Q